Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3276086 | 0.83 | L3MBTL1 (0.61) | L3MBTL1TDP1ATMNPSR1ALDH1A1 | |
| SCHEMBL5476076 | 0.80 | ALDH1A1 (0.31) | L3MBTL1NPSR1ALDH1A1HPGDMAPT | |
| SCHEMBL27536175 | 0.79 | MEN1 (0.41) | L3MBTL1TDP1ATMNPSR1ALDH1A1 | |
| SCHEMBL27562712 | 0.79 | ALDH1A1 (0.50) | L3MBTL1ALDH1A1HPGDMAPTHSD17B10 | |
| SCHEMBL5696331 | 0.78 | L3MBTL1 (0.49) | L3MBTL1TDP1ATMNPSR1ALDH1A1 | |
| SCHEMBL9615375 | 0.78 | MTNR1A (0.51) | NPSR1TSHR | |
| SCHEMBL15518610 | 0.78 | L3MBTL1 (0.66) | L3MBTL1TDP1ATMNPSR1ALDH1A1 | |
| SCHEMBL5669591 | 0.77 | MAPT (0.44) | L3MBTL1TDP1NPSR1ALDH1A1HPGD | |
| SCHEMBL27502541 | 0.77 | NPSR1 (0.40) | L3MBTL1TDP1ATMNPSR1ALDH1A1 | |
| SCHEMBL2559709 | 0.77 | ALDH1A1 (0.50) | TDP1ALDH1A1HPGDTSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106257976-A | Human plasma kallikrein inhibitors | 拜奥克里斯特制药公司 | 2016-12-28 | — | — | CN | disclosed |