Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27262053 | 0.82 | LMNA (0.64) | KMT2ALMNAMAPTALDH1A1MEN1 | |
| SCHEMBL5550802 | 0.77 | MAPT (0.56) | KMT2ALMNAMAPTALDH1A1MEN1 | |
| SCHEMBL5550024 | 0.75 | MAPT (0.55) | KMT2ALMNAMAPTALDH1A1MEN1 | |
| SCHEMBL5550676 | 0.73 | MAPT (0.46) | KMT2ALMNAMAPTALDH1A1MEN1 | |
| SCHEMBL5550840 | 0.71 | KMT2A (0.47) | KMT2ALMNAMAPTALDH1A1MEN1 | |
| SCHEMBL5550036 | 0.69 | KMT2A (0.45) | KMT2ALMNAMAPTALDH1A1MEN1 | |
| SCHEMBL5547460 | 0.68 | ALOX5 (0.46) | KMT2ALMNAMAPTALDH1A1MEN1 | |
| SCHEMBL28436223 | 0.67 | LMNA (0.47) | KMT2ALMNAALDH1A1HTTTSHR | |
| SCHEMBL5551976 | 0.67 | MAPT (0.46) | KMT2ALMNAMAPTALDH1A1MEN1 | |
| SCHEMBL5546266 | 0.66 | EGFR (0.46) | KMT2ALMNAMAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106432202-A | Quinazoline derivative and application thereof | 郑州大学第附属医院 | 2017-02-22 | — | — | CN | disclosed |