Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | MMP13 | P45452 | 1/20 | 0.53 |
| ▸ | DCTPP1 | Q9H773 | 6/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | DHODH | Q02127 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | NAMPT | P43490 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28111329 | 0.87 | DCTPP1 (0.65) | SCDMMP13DCTPP1 | |
| SCHEMBL28111205 | 0.80 | DCTPP1 (0.63) | SCDDCTPP1SMN1; SMN2 | |
| SCHEMBL3226700 | 0.80 | SCD (0.62) | SCDHTTMMP13DCTPP1 | |
| SCHEMBL3226709 | 0.80 | SCD (0.62) | SCDHTTMMP13DCTPP1 | |
| SCHEMBL30077095 | 0.75 | PRKCA (0.52) | SCDALDH1A1HTTMMP13LMNA | |
| SCHEMBL15347473 | 0.75 | PRKCA (0.52) | SCDALDH1A1HTTMMP13LMNA | |
| SCHEMBL29859847 | 0.74 | SMN1; SMN2 (0.59) | ALDH1A1HTTKMT2ASMN1; SMN2 | |
| SCHEMBL28836616 | 0.73 | SCD (0.52) | SCDNAMPT | |
| SCHEMBL28111734 | 0.72 | NAMPT (0.49) | SCDALDH1A1DCTPP1SMN1; SMN2NAMPT | |
| SCHEMBL28111232 | 0.72 | HTT (0.58) | ALDH1A1HTTMMP13RECQLKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106187910-A | Pyridazine class derivant and its production and use | 浙江大学 | 2016-12-07 | — | — | CN | claimed |
| CN-106187910-A | Pyridazine class derivant and its production and use | 浙江大学 | 2016-12-07 | — | — | CN | disclosed |