Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.49 |
| ▸ | SCD | O00767 | 4/20 | 0.48 |
| ▸ | NAPEPLD | Q6IQ20 | 3/20 | 0.47 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28836616 | 0.96 | SCD (0.52) | NAMPTSCDNAPEPLD | |
| SCHEMBL939100 | 0.89 | NAPEPLD (0.48) | NAMPTSCDNAPEPLDDCTPP1 | |
| SCHEMBL1377378 | 0.78 | SCD (0.79) | SCDDCTPP1 | |
| SCHEMBL28111774 | 0.77 | HSD11B1 (0.66) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL936722 | 0.77 | SCD (0.59) | SCD | |
| SCHEMBL28111329 | 0.77 | DCTPP1 (0.65) | SCDDCTPP1 | |
| SCHEMBL12843981 | 0.76 | CNR1 (0.53) | NAMPTHDAC6 | |
| SCHEMBL28111205 | 0.75 | DCTPP1 (0.63) | SCDDCTPP1SMN1; SMN2 | |
| SCHEMBL1380904 | 0.74 | SCD (0.70) | SCD | |
| SCHEMBL12844005 | 0.74 | NAMPT (0.51) | NAMPTHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106187910-A | Pyridazine class derivant and its production and use | 浙江大学 | 2016-12-07 | — | — | CN | claimed |
| CN-106187910-A | Pyridazine class derivant and its production and use | 浙江大学 | 2016-12-07 | — | — | CN | disclosed |