Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | MMP13 | P45452 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | NAMPT | P43490 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28111733 | 0.89 | MMP13 (0.52) | MMP13KMT2ASMN1; SMN2RAB9ARECQL | |
| SCHEMBL28111776 | 0.81 | MAPT (0.64) | HTTMMP13KMT2AHPGDALDH1A1 | |
| SCHEMBL29818253 | 0.78 | KMT2A (0.52) | HTTUSP2KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL28836629 | 0.78 | VNN1 (0.56) | MMP13KMT2ASMN1; SMN2RAB9ARECQL | |
| SCHEMBL28111242 | 0.77 | RAB9A (0.53) | HTTUSP2MMP13POLBKMT2A | |
| SCHEMBL1161997 | 0.75 | NAMPT (0.75) | HTTUSP2MMP13KMT2AALDH1A1 | |
| SCHEMBL29800992 | 0.74 | HTT (1.00) | HTTUSP2MMP13POLBKMT2A | |
| SCHEMBL16598258 | 0.72 | HTT (0.76) | HTTUSP2MMP13POLBKMT2A | |
| SCHEMBL11614852 | 0.72 | SMN1; SMN2 (0.81) | HTTPOLBKMT2ASMN1; SMN2TSHR | |
| SCHEMBL28111207 | 0.72 | SCD (0.65) | HTTMMP13POLBKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106187910-A | Pyridazine class derivant and its production and use | 浙江大学 | 2016-12-07 | — | — | CN | claimed |
| CN-106187910-A | Pyridazine class derivant and its production and use | 浙江大学 | 2016-12-07 | — | — | CN | disclosed |