Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | AGER | Q15109 | 3/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL433534 | 0.79 | G6PC1 (0.38) | SMN1; SMN2LMNAAGERMTNR1AMAPK1 | |
| SCHEMBL8808223 | 0.73 | SMN1; SMN2 (0.58) | SMN1; SMN2LMNAMAPK1ALDH1A1KDM4E | |
| SCHEMBL9057974 | 0.70 | G6PC1 (0.42) | SMN1; SMN2LMNAAGERMTNR1AMAPK1 | |
| SCHEMBL9057644 | 0.70 | G6PC1 (0.42) | SMN1; SMN2LMNAAGERMTNR1AMAPK1 | |
| SCHEMBL4476467 | 0.69 | G6PC1 (0.54) | SMN1; SMN2AGERMTNR1AMAPK1L3MBTL1 | |
| SCHEMBL10891206 | 0.69 | G6PC1 (0.50) | SMN1; SMN2AGERMTNR1AMAPK1ALDH1A1 | |
| SCHEMBL6658628 | 0.68 | AGER (0.41) | SMN1; SMN2LMNAAGERMTNR1AMAPK1 | |
| SCHEMBL2814615 | 0.68 | AGER (0.67) | SMN1; SMN2AGERMTNR1AMAPK1L3MBTL1 | |
| SCHEMBL9057107 | 0.68 | G6PC1 (0.40) | SMN1; SMN2LMNAAGERMTNR1AMAPK1 | |
| Carbamic Acid SCHEMBL28311097 | 0.68 | AGER (0.46) | SMN1; SMN2LMNAAGERMTNR1AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106187910-A | Pyridazine class derivant and its production and use | 浙江大学 | 2016-12-07 | — | — | CN | claimed |
| CN-106187910-A | Pyridazine class derivant and its production and use | 浙江大学 | 2016-12-07 | — | — | CN | disclosed |