Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | G6PC1 | P35575 | 1/20 | 0.42 |
| ▸ | AGER | Q15109 | 3/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9057644 | 1.00 | G6PC1 (0.42) | G6PC1AGERMTNR1ASLC6A2SLC6A4 | |
| SCHEMBL28291417 | 0.80 | S1PR1 (0.37) | LMNAMAPK1L3MBTL1 | |
| SCHEMBL8808223 | 0.78 | SMN1; SMN2 (0.58) | G6PC1SLC6A2SLC6A4SLC6A3LMNA | |
| SCHEMBL9057107 | 0.77 | G6PC1 (0.40) | G6PC1AGERMTNR1ASLC6A2SLC6A4 | |
| SCHEMBL4476467 | 0.76 | G6PC1 (0.54) | G6PC1AGERMTNR1ASLC6A2SLC6A4 | |
| SCHEMBL10891206 | 0.76 | G6PC1 (0.50) | G6PC1AGERMTNR1ASLC6A2SLC6A4 | |
| SCHEMBL433534 | 0.72 | G6PC1 (0.38) | G6PC1AGERMTNR1ASLC6A2SLC6A4 | |
| SCHEMBL6658628 | 0.72 | AGER (0.41) | G6PC1AGERMTNR1ASLC6A2SLC6A4 | |
| SCHEMBL9057205 | 0.72 | G6PC1 (0.39) | G6PC1AGERMTNR1ASLC6A2SLC6A4 | |
| SCHEMBL4973167 | 0.72 | HCAR3 (0.50) | SLC6A2SLC6A4SLC6A3LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996010559-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-04-11 | — | — | WO | disclosed |