Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP3 | O14638 | 6/20 | 0.54 |
| ▸ | ENPP2 | Q13822 | 5/20 | 0.54 |
| ▸ | ENPP1 | P22413 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27732963 | 0.83 | ENPP3 (0.55) | ENPP3ENPP2ENPP1MAPTKMT2A | |
| SCHEMBL5510733 | 0.81 | ENPP3 (0.51) | ENPP3ENPP2ENPP1MAPTKMT2A | |
| SCHEMBL28074505 | 0.78 | ENPP3 (0.40) | ENPP3ENPP2ENPP1MAPTKMT2A | |
| SCHEMBL9538667 | 0.78 | ENPP3 (0.41) | ENPP3ENPP2ENPP1MAPTKMT2A | |
| SCHEMBL11248469 | 0.77 | ALDH1A1 (0.50) | ENPP3ENPP2ENPP1MAPTKMT2A | |
| SCHEMBL27793994 | 0.76 | MEN1 (0.46) | ENPP3ENPP2ENPP1MAPTKMT2A | |
| SCHEMBL14779304 | 0.74 | ENPP3 (0.47) | ENPP3ENPP2ENPP1KMT2AALDH1A1 | |
| SCHEMBL18007730 | 0.73 | F2 (0.50) | KMT2AALDH1A1MEN1 | |
| SCHEMBL14780378 | 0.73 | ENPP3 (0.48) | ENPP3ENPP2ENPP1KMT2AALDH1A1 | |
| SCHEMBL4774121 | 0.73 | KMT2A (0.75) | ENPP3ENPP2ENPP1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106132931-B | Carbocyclic ring sulfone ROR gamma modulators | 百时美施贵宝公司 | 2019-08-02 | — | — | CN | disclosed |
| CN-106132931-A | Carbocyclic ring sulfone ROR gamma modulators | 百时美施贵宝公司 | 2016-11-16 | — | — | CN | disclosed |