Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP3 | O14638 | 4/20 | 0.41 |
| ▸ | ENPP1 | P22413 | 3/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.41 |
| ▸ | HTR6 | P50406 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | SCN4A | P35499 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28074505 | 0.93 | ENPP3 (0.40) | ENPP3ENPP1ENPP2HTR2CHTR2B | |
| SCHEMBL3060996 | 0.86 | ENPP3 (0.41) | ENPP3ENPP1ENPP2HTR6SCN4A | |
| SCHEMBL3803839 | 0.86 | ENPP3 (0.41) | ENPP3ENPP1ENPP2HTR6SCN4A | |
| SCHEMBL7404085 | 0.86 | ELANE (0.43) | ENPP3ENPP1ENPP2HTR6HTR2C | |
| SCHEMBL8301422 | 0.86 | ELANE (0.43) | ENPP3ENPP1ENPP2HTR6HTR2C | |
| SCHEMBL8212865 | 0.84 | DPP4 (0.45) | HTR6KDM4EGAAALDH1A1 | |
| SCHEMBL27539865 | 0.82 | KMT2A (0.44) | ENPP3ENPP1ENPP2ALDH1A1KMT2A | |
| SCHEMBL5717063 | 0.82 | ENPP3 (0.46) | ENPP3ENPP1ENPP2MAPTGAA | |
| SCHEMBL3084068 | 0.79 | CA12 (0.52) | MAPTKDM4EGAAMEN1ALDH1A1 | |
| SCHEMBL20400865 | 0.78 | NOS2 (0.33) | HTR2CHTR2BSCN4AELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993005014-A1 | AROMATIC SULFONAMIDE DERIVATIVES, THEIR USE AS ENZYME INHIBITORS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | PHARNO-WEDROPHARM GMBH (DE) | 1993-03-18 | — | — | WO | disclosed |