Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP3 | O14638 | 4/20 | 0.40 |
| ▸ | ENPP1 | P22413 | 3/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.40 |
| ▸ | F2 | P00734 | 2/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9538667 | 0.93 | ENPP3 (0.41) | ENPP3ENPP1ENPP2CA12CA9 | |
| SCHEMBL3060996 | 0.78 | ENPP3 (0.41) | ENPP3ENPP1ENPP2 | |
| SCHEMBL3803839 | 0.78 | ENPP3 (0.41) | ENPP3ENPP1ENPP2 | |
| SCHEMBL28111238 | 0.78 | ENPP3 (0.54) | ENPP3ENPP1ENPP2L3MBTL1MAPT | |
| SCHEMBL8301422 | 0.78 | ELANE (0.43) | ENPP3ENPP1ENPP2KMT2AKDM4E | |
| SCHEMBL7404085 | 0.78 | ELANE (0.43) | ENPP3ENPP1ENPP2KMT2AKDM4E | |
| SCHEMBL5717063 | 0.77 | ENPP3 (0.46) | ENPP3ENPP1ENPP2MAPTMMP2 | |
| SCHEMBL27539865 | 0.77 | KMT2A (0.44) | ENPP3ENPP1ENPP2KMT2A | |
| SCHEMBL8212865 | 0.76 | DPP4 (0.45) | MMP1MMP2MMP9MMP8MMP13 | |
| SCHEMBL15775888 | 0.71 | CA1 (0.43) | CA12CA1CA2KDM4EHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105612153-A | Substituted sulfonamide compounds as TRPA1 conditioner | HOFFMANN LA ROCHE | 2016-05-25 | — | — | CN | disclosed |