Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.34 |
| ▸ | TUBB | P07437 | 4/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.34 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.34 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.34 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.34 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.34 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.34 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.34 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.34 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6793154 | 0.94 | LMNA (0.40) | LMNASMN1; SMN2HSD17B3KDM4EKMT2A | |
| SCHEMBL6783071 | 0.76 | KDM4E (0.51) | LMNASMN1; SMN2KDM4EKMT2APOLB | |
| SCHEMBL1589975 | 0.71 | ALDH1A1 (0.44) | SMN1; SMN2KDM4ETDP1MAPT | |
| Ethoxycarbonyl Group SCHEMBL28016264 | 0.71 | MAPT (0.33) | LMNASMN1; SMN2KDM4EKMT2APOLB | |
| SCHEMBL6787091 | 0.71 | ATM (0.41) | LMNASMN1; SMN2HSD17B3KDM4EKMT2A | |
| SCHEMBL7814302 | 0.70 | TPMT (0.41) | LMNAKDM4EKMT2APOLBTDP1 | |
| SCHEMBL6794084 | 0.70 | ALDH1A1 (0.55) | LMNAKDM4EKMT2ATDP1MEN1 | |
| SCHEMBL6785629 | 0.68 | SMN1; SMN2 (0.35) | LMNASMN1; SMN2KDM4EKMT2APOLB | |
| SCHEMBL14823524 | 0.67 | KDM4E (0.43) | LMNAKDM4EKMT2APOLBTDP1 | |
| SCHEMBL9621166 | 0.65 | ATM (0.41) | LMNASMN1; SMN2KDM4EKMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104649879-B | Substituted benzene methylene 1,2,3,4-Tetrahydrooxonaphthalene analog derivative and preparation method, application | 中国人民解放军第二军医大学 | 2017-01-04 | — | — | CN | claimed |
| CN-104649879-B | Substituted benzene methylene 1,2,3,4-Tetrahydrooxonaphthalene analog derivative and preparation method, application | 中国人民解放军第二军医大学 | 2017-01-04 | — | — | CN | disclosed |