Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.32 |
| ▸ | TUBB | P07437 | 1/20 | 0.32 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.32 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.32 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.32 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.32 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.32 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.32 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.32 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.32 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.32 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.32 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.32 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.32 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6793154 | 0.73 | LMNA (0.40) | MAPTERN1TUBB4ATUBBTUBA3C | |
| Methylene Chloride SCHEMBL28111275 | 0.71 | LMNA (0.36) | MAPTERN1TUBB4ATUBBTUBA3C | |
| SCHEMBL7814302 | 0.69 | TPMT (0.41) | MAPTMEN1KMT2AKDM4ETDP1 | |
| SCHEMBL6783071 | 0.67 | KDM4E (0.51) | MEN1KMT2AKDM4ETDP1LMNA | |
| SCHEMBL14823524 | 0.63 | KDM4E (0.43) | MAPTMEN1KMT2AKDM4ETDP1 | |
| Guaiacol SCHEMBL28300008 | 0.62 | TP53 (0.62) | MAPTTSHRERN1TUBB1MEN1 | |
| Ethoxycarbonyl Group SCHEMBL27636148 | 0.61 | ALDH1A1 (0.39) | MAPTTSHRERN1MEN1KMT2A | |
| SCHEMBL1771325 | 0.60 | TUBB4A (0.46) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL6782949 | 0.60 | TUBB4A (0.40) | MAPTTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL8395 | 0.59 | PTGS2 (0.53) | MAPTTUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104649879-B | Substituted benzene methylene 1,2,3,4-Tetrahydrooxonaphthalene analog derivative and preparation method, application | 中国人民解放军第二军医大学 | 2017-01-04 | — | — | CN | claimed |
| CN-104649879-A | Substituted benzylidene tetralone derivatives and preparation method and applications | UNIV PLA 2ND MILITARY MEDICAL | 2015-05-27 | — | — | CN | claimed |
| CN-104649879-B | Substituted benzene methylene 1,2,3,4-Tetrahydrooxonaphthalene analog derivative and preparation method, application | 中国人民解放军第二军医大学 | 2017-01-04 | — | — | CN | disclosed |
| CN-104649879-A | Substituted benzylidene tetralone derivatives and preparation method and applications | UNIV PLA 2ND MILITARY MEDICAL | 2015-05-27 | — | — | CN | disclosed |