Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | KIT | P10721 | 2/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27828569 | 0.83 | MKNK1 (0.43) | TP53METAP2NPC1RAB9AMEN1 | |
| SCHEMBL695299 | 0.83 | METAP2 (0.37) | ALDH1A1METAP2HSD17B10NPC1RAB9A | |
| SCHEMBL2379590 | 0.83 | ALOX15 (0.48) | ALDH1A1HSD17B10NPC1RAB9AMEN1 | |
| SCHEMBL544500 | 0.83 | ALOX15 (0.48) | ALDH1A1HSD17B10NPC1RAB9AMEN1 | |
| SCHEMBL10775547 | 0.79 | ALDH1A1 (0.39) | CYP3A4ALDH1A1TDP1TP53METAP2 | |
| SCHEMBL6155891 | 0.79 | PDE3B (0.39) | CYP3A4ALDH1A1TDP1TP53METAP2 | |
| SCHEMBL22637221 | 0.79 | SMN1; SMN2 (0.46) | TDP1TP53METAP2PDGFRBTAAR1 | |
| SCHEMBL32670854 | 0.79 | ALDH1A1 (0.39) | ALDH1A1PDGFRBFGFR1FLT3 | |
| SCHEMBL27568104 | 0.77 | ERBB2 (0.49) | ALDH1A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL27875387 | 0.75 | ADORA2A (0.38) | ALDH1A1MAPTKDM4ESMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103717602-B | Kinase inhibitors | 加利福尼亚大学董事会 | 2016-11-09 | — | — | CN | disclosed |