SCHEMBL28111368

SCHEMBL28111368

CCC(CC)C(=O)ON1CCCCC1OCc1ncccc1-c1ccc(Cl)cc1

nearest known ligand 0.35

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TBXA2R P21731 1/20 0.35
CHRM3 P20309 2/20 0.35
GPR119 Q8TDV5 2/20 0.34
CNR1 P21554 3/20 0.33
POLB P06746 1/20 0.33
NPSR1 Q6W5P4 2/20 0.33
FAAH O00519 2/20 0.33
GRIN2B Q13224 1/20 0.33
CPT1A P50416 1/20 0.32
GAA P10253 1/20 0.32
HPGD P15428 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28832706 0.84 TBXA2R (0.34) TBXA2RCHRM3GPR119CNR1NPSR1
SCHEMBL28087406 0.70 KCNK3 (0.37) TBXA2RGPR119FAAH
SCHEMBL28081660 0.67 CYP2C19 (0.37) TBXA2RPOLBNPSR1HPGD
SCHEMBL1287484 0.66 BCHE (0.47) TBXA2R
SCHEMBL15467458 0.65 SLC6A2 (0.41) CHRM3
SCHEMBL791815 0.64 NPC1 (0.40) NPSR1
Acetic Acid SCHEMBL28296133 0.63 TDP1 (0.46)
SCHEMBL17066980 0.63 TDP1 (0.41) POLB
SCHEMBL5516950 0.62 ALDH1A1 (0.52)
SCHEMBL8727056 0.62 BCHE (0.44) TBXA2RCHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106188002-A A kind of substituted piperidine base ethyl n-butyrate. quaternary ammonium salt and preparation method thereof 重庆华邦制药有限公司 2016-12-07 CN disclosed