Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13593519 | 0.83 | LMNA (0.63) | ALDH1A1HSD17B10LMNAKMT2AMEN1 | |
| SCHEMBL4899583 | 0.81 | APEX1 (0.69) | ALDH1A1HSD17B10LMNAKMT2AMEN1 | |
| SCHEMBL6089289 | 0.81 | ALDH1A1 (0.61) | ALDH1A1HSD17B10LMNAKMT2AMEN1 | |
| SCHEMBL9528244 | 0.80 | CYP1A2 (0.57) | ALDH1A1HSD17B10LMNAKMT2AMEN1 | |
| SCHEMBL10686326 | 0.80 | ALDH1A1 (0.60) | ALDH1A1HSD17B10LMNAKMT2AMEN1 | |
| SCHEMBL7403091 | 0.79 | LMNA (0.59) | ALDH1A1HSD17B10LMNAKMT2AMEN1 | |
| SCHEMBL3453667 | 0.79 | ALDH1A1 (0.50) | ALDH1A1HSD17B10LMNAKMT2AMEN1 | |
| SCHEMBL14441334 | 0.79 | ALDH1A1 (0.50) | ALDH1A1HSD17B10LMNAKMT2AMEN1 | |
| Acetic Acid SCHEMBL9528247 | 0.79 | ALDH1A1 (0.55) | ALDH1A1HSD17B10LMNAKMT2AMEN1 | |
| SCHEMBL11354000 | 0.77 | ALDH1A1 (0.65) | ALDH1A1HSD17B10LMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106074497-A | Butyphthalide and derivant application in Parkinsonian medicine is treated in preparation thereof | 石药集团恩必普药业有限公司 | 2016-11-09 | — | — | CN | disclosed |