Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | CNR2 | P34972 | 13/20 | 0.54 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28836629 | 0.81 | VNN1 (0.56) | CNR2DGAT1 | |
| SCHEMBL28111211 | 0.78 | MT-CO2 (0.52) | POLBCNR2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL28111270 | 0.78 | CNR2 (0.60) | POLBCNR2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL938902 | 0.75 | NAMPT (0.47) | NAMPT | |
| SCHEMBL5214258 | 0.74 | CNR2 (0.91) | CNR2CYP3A4CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL5214314 | 0.74 | CNR2 (0.75) | CNR2EPHX1EPHX2CYP3A4CYP2C9 | |
| SCHEMBL5212538 | 0.74 | CNR2 (0.93) | CNR2CYP3A4CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL5212134 | 0.74 | CNR2 (0.75) | CNR2EPHX1EPHX2CYP3A4CYP2C9 | |
| SCHEMBL5214918 | 0.73 | CNR2 (0.69) | POLBCNR2EPHX1EPHX2CYP3A4 | |
| SCHEMBL5216408 | 0.73 | CNR2 (0.75) | CNR2EPHX1EPHX2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106187910-A | Pyridazine class derivant and its production and use | 浙江大学 | 2016-12-07 | — | — | CN | claimed |
| CN-106187910-A | Pyridazine class derivant and its production and use | 浙江大学 | 2016-12-07 | — | — | CN | disclosed |