Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VNN1 | O95497 | 1/20 | 0.56 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.55 |
| ▸ | CNR2 | P34972 | 3/20 | 0.52 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28111270 | 0.90 | CNR2 (0.60) | VNN1MT-CO2CNR2DGAT1LMNA | |
| SCHEMBL28111211 | 0.90 | MT-CO2 (0.52) | VNN1MT-CO2CNR2DGAT1MAPT | |
| SCHEMBL28111733 | 0.88 | MMP13 (0.52) | MT-CO2CNR2LMNAHPGDKDM4E | |
| SCHEMBL28111776 | 0.87 | MAPT (0.64) | VNN1CNR2LMNAHPGDPLA2G1B | |
| SCHEMBL28111735 | 0.81 | POLB (0.56) | CNR2DGAT1 | |
| SCHEMBL28111232 | 0.78 | HTT (0.58) | HPGDSMN1; SMN2NPSR1KMT2ARECQL | |
| SCHEMBL5457653 | 0.77 | CNR2 (0.74) | MT-CO2CNR2 | |
| SCHEMBL5077144 | 0.73 | CNR2 (0.81) | CNR2 | |
| SCHEMBL5452563 | 0.73 | CNR2 (0.84) | MT-CO2CNR2 | |
| SCHEMBL7423285 | 0.72 | MTOR (0.79) | LMNAHPGDPLA2G1BMAOBATG4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106187910-A | Pyridazine class derivant and its production and use | 浙江大学 | 2016-12-07 | — | — | CN | claimed |
| CN-106187910-A | Pyridazine class derivant and its production and use | 浙江大学 | 2016-12-07 | — | — | CN | disclosed |