Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 8/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.46 |
| ▸ | VNN1 | O95497 | 1/20 | 0.45 |
| ▸ | MTOR | P42345 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28836629 | 0.90 | VNN1 (0.56) | CNR2RAB9AMEN1LMNAMAPT | |
| SCHEMBL28111211 | 0.89 | MT-CO2 (0.52) | CNR2RAB9ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL28111735 | 0.78 | POLB (0.56) | CNR2CYP1A2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL28111733 | 0.77 | MMP13 (0.52) | CNR2RAB9ACYP1A2CYP2C19CYP2D6 | |
| SCHEMBL28111776 | 0.77 | MAPT (0.64) | CNR2CYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL5459863 | 0.76 | CNR2 (0.81) | CNR2RAB9ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL5078904 | 0.75 | CNR2 (1.00) | CNR2RAB9ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL6379713 | 0.71 | TP53 (0.57) | RAB9ACYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL5083343 | 0.71 | CNR2 (1.00) | CNR2CYP1A2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL5457653 | 0.70 | CNR2 (0.74) | CNR2CYP1A2CYP2C9CYP2C19CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106187910-A | Pyridazine class derivant and its production and use | 浙江大学 | 2016-12-07 | — | — | CN | claimed |
| CN-106187910-A | Pyridazine class derivant and its production and use | 浙江大学 | 2016-12-07 | — | — | CN | disclosed |