Benzophenone

Benzophenone

SCHEMBL28111773

CCC(=O)CC.O=C(c1ccccc1)c1ccccc1

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.67
RAB9A P51151 5/20 0.58
HPGD P15428 4/20 0.58
ELANE P08246 2/20 0.58
L3MBTL1 Q9Y468 3/20 0.56
ATM Q13315 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
SRD5A2 P31213 1/20 0.56
CES2 O00748 1/20 0.56
CES1 P23141 1/20 0.56
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
NPC1 O15118 1/20 0.52
LMNA P02545 2/20 0.52
SMN1; SMN2 Q16637 2/20 0.49
MAPT P10636 2/20 0.49
GAA P10253 1/20 0.49
HTT P42858 1/20 0.49
HSD11B1 P28845 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzophenone SCHEMBL27621952 0.88 ALDH1A1 (0.70) ALDH1A1RAB9AHPGDELANEL3MBTL1
Benzophenone SCHEMBL27461157 0.88 ALDH1A1 (0.70) ALDH1A1RAB9AHPGDELANEL3MBTL1
Benzophenone SCHEMBL8089683 0.87 ALDH1A1 (0.78) ALDH1A1RAB9AHPGDELANEL3MBTL1
Benzil SCHEMBL28136493 0.86 CES2 (0.68) ALDH1A1RAB9ATDP1CES2CES1
Benzophenone SCHEMBL6910177 0.86 ALDH1A1 (0.67) ALDH1A1RAB9AHPGDELANEL3MBTL1
Benzophenone SCHEMBL11693944 0.85 ALDH1A1 (0.74) ALDH1A1RAB9AHPGDELANEL3MBTL1
Benzophenone SCHEMBL21082732 0.85 ALDH1A1 (0.74) ALDH1A1RAB9AHPGDELANEL3MBTL1
Benzophenone SCHEMBL5817628 0.85 ALDH1A1 (0.74) ALDH1A1RAB9AHPGDELANEL3MBTL1
Acetophenone SCHEMBL9142608 0.84 SMN1; SMN2 (0.56) ALDH1A1RAB9AHPGDL3MBTL1ATM
Benzophenone SCHEMBL8930056 0.84 L3MBTL1 (0.67) ALDH1A1RAB9AHPGDELANEL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110423297-A Asymmetric transition-metal catalyst of a kind of [C^N^O] three tooth chelating and preparation method thereof UNIV NANCHANG 2019-11-08 CN claimed
CN-110423297-A Asymmetric transition-metal catalyst of a kind of [C^N^O] three tooth chelating and preparation method thereof UNIV NANCHANG 2019-11-08 CN disclosed
CN-106147973-A Characteristic of metal cutting fluid 苏州天允金属材料有限公司 2016-11-23 CN disclosed