Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27521615 | 0.93 | ALDH1A1 (0.40) | LMNASMN1; SMN2ALDH1A1PKMHTT | |
| SCHEMBL6624655 | 0.84 | L3MBTL1 (0.41) | SMN1; SMN2ALDH1A1PKMHTTKMT2A | |
| SCHEMBL27939942 | 0.84 | ALDH1A1 (0.46) | LMNASMN1; SMN2ALDH1A1HTTKMT2A | |
| SCHEMBL2155976 | 0.83 | PKM (0.36) | LMNASMN1; SMN2ALDH1A1PKMHTT | |
| SCHEMBL2041342 | 0.80 | PKM (0.42) | LMNASMN1; SMN2ALDH1A1PKMHTT | |
| SCHEMBL27911956 | 0.80 | PLA2G4A (0.51) | LMNASMN1; SMN2TSHRALDH1A1PKM | |
| SCHEMBL10716648 | 0.79 | MEN1 (0.36) | LMNAALDH1A1PKMHTTKMT2A | |
| SCHEMBL1219078 | 0.79 | PKM (0.38) | LMNASMN1; SMN2ALDH1A1PKMHTT | |
| SCHEMBL11688470 | 0.79 | PKM (0.38) | LMNASMN1; SMN2ALDH1A1PKMHTT | |
| SCHEMBL4755861 | 0.79 | ALDH1A1 (0.38) | LMNASMN1; SMN2TSHRALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106045937-B | A kind of synthetic method of { 2- [2- (2- amino -4- thiazolyl)-acetyl-amino] -4- thiazolyl }-acetic acid | 杭州诺维和医药技术有限公司 | 2019-04-16 | — | — | CN | disclosed |
| CN-106045937-A | Synthesizing method of {2-[2-(2-amino-4-thiazolyl)-amino acetyl]-4-thiazolyl}-acetic acid | 杭州诺维和医药技术有限公司 | 2016-10-26 | — | — | CN | disclosed |