Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM6 | O15303 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.34 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | LHCGR | P22888 | 1/20 | 0.31 |
| ▸ | CISD2 | Q8N5K1 | 1/20 | 0.31 |
| ▸ | HPGDS | O60760 | 1/20 | 0.31 |
| ▸ | CDC7 | O00311 | 1/20 | 0.31 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.31 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28273199 | 0.86 | GFER (0.36) | GRM6GFERALDH1A1HPGDLMNA | |
| SCHEMBL27788513 | 0.82 | LMNA (0.56) | ALDH1A1HPGDLMNAMAPTSMN1; SMN2 | |
| SCHEMBL4297234 | 0.81 | ALDH1A1 (0.32) | GRM6ALDH1A1HPGDTSHRHPGDS | |
| SCHEMBL4686476 | 0.77 | GRM6 (0.40) | GRM6ALDH1A1HPGDLMNAMAPT | |
| SCHEMBL27731140 | 0.76 | ALDH1A1 (0.35) | GRM6ALDH1A1HPGDMAPTKDM4E | |
| SCHEMBL27891114 | 0.75 | GRM6 (0.56) | GRM6ALDH1A1HPGDLMNAMAPT | |
| Ammonia Solution, Strong SCHEMBL29139499 | 0.73 | LCK (0.36) | ALDH1A1HPGDMAPTNPC1RAB9A | |
| SCHEMBL28861577 | 0.73 | LMNA (0.42) | GRM6GFERALDH1A1HPGDLMNA | |
| SCHEMBL27638360 | 0.73 | GRM6 (0.41) | GRM6ALDH1A1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL27340438 | 0.72 | GRM6 (0.38) | GRM6ALDH1A1HPGDADORA1CISD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118994050-A | Dasatinib intermediate Synthesis method of intermediate | 扬州市普林斯医药科技有限公司 | 2024-11-22 | — | — | CN | disclosed |
| CN-106279061-A | A kind of method preparing Dasatinib intermediate | 上海科胜药物研发有限公司 | 2017-01-04 | — | — | CN | disclosed |