Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM6 | O15303 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | COPS5 | Q92905 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.31 |
| ▸ | HPGD | P15428 | 3/20 | 0.31 |
| ▸ | CISD2 | Q8N5K1 | 1/20 | 0.31 |
| ▸ | HPGDS | O60760 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27340438 | 0.88 | GRM6 (0.38) | GRM6ADORA1ALDH1A1HPGDCISD2 | |
| SCHEMBL27754067 | 0.86 | GRM6 (0.36) | GRM6ALDH1A1HPGDCISD2 | |
| SCHEMBL11264947 | 0.83 | GRM6 (0.35) | GRM6 | |
| SCHEMBL27703537 | 0.82 | ALDH1A1 (0.49) | ADORA1ALDH1A1HPGDSMN1; SMN2HSD17B10 | |
| Hydrochloric Acid SCHEMBL11273202 | 0.82 | GRM6 (0.34) | GRM6 | |
| SCHEMBL4305446 | 0.81 | GRM6 (0.31) | GRM6ALDH1A1HPGDSLMNA | |
| SCHEMBL9703895 | 0.81 | GRM6 (0.34) | GRM6LMNAGAAMAPT | |
| SCHEMBL3589425 | 0.80 | COPS5 (0.36) | GRM6COPS5 | |
| SCHEMBL27638360 | 0.80 | GRM6 (0.41) | GRM6ADORA1ALDH1A1HPGDCISD2 | |
| SCHEMBL9446743 | 0.80 | GRM6 (0.33) | GRM6ALDH1A1HPGDCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118047768-A | Oligostat analogue and antiviral application thereof | 华中农业大学 | 2024-05-17 | — | — | CN | disclosed |
| CN-1938279-B | Modulators of atp-binding cassette transporters | VERTEX PHARMA CO LTD | 2011-09-14 | — | — | CN | disclosed |
| CN-101023079-B | Substituted hydantoins for the treatment of cancer | HOFFMANN LA ROCHE | 2010-05-05 | — | — | CN | disclosed |
| CN-101351457-A | Insecticidal 2-acylaminothiazole-4-carboxamides | BAYER CROPSCIENCE AG (DE) | 2009-01-21 | — | — | CN | disclosed |
| EP-1963290-A1 | INSECTICIDAL 2 -ACYLAMINOTHIAZOLE-4 -CARBOXAMIDES | Bayer CropScience Aktiengesellschaft (DE) | 2008-09-03 | — | — | EP | disclosed |
| US-20080039499-A1 | Chemical Compounds | BOWER JUSTIN F | 2008-02-14 | — | — | US | disclosed |
| CN-101023079-A | Substituted hydantoins for the treatment of cancer | HOFFMANN LA ROCHE (CH) | 2007-08-22 | — | — | CN | disclosed |
| CN-101006085-A | Substituted hydantoins | HOFFMANN LA ROCHE (CH) | 2007-07-25 | — | — | CN | disclosed |
| CN-1993358-A | Thiazole derivatives as chemokine receptor antagonists | ASTRAZENECA AB (SE) | 2007-07-04 | — | — | CN | disclosed |
| WO-2007051560-A1 | INSECTICIDAL 2 -ACYLAMINOTHIAZOLE-4 -CARBOXAMIDES | BAYER CROPSCIENCE AG (DE) | 2007-05-10 | — | — | WO | disclosed |
| CN-1938279-A | Modulators of atp-binding cassette transporters | VERTEX PHARMA (US) | 2007-03-28 | — | — | CN | disclosed |
| EP-1761526-A2 | THIAZOLE DERIVATIVES AS CHEMOKINE RECEPTOR ANTAGONISTS | AstraZeneca AB (SE) | 2007-03-14 | — | — | EP | disclosed |
| WO-2005118579-A2 | THIAZOLE DERIVATIVES AS CHEMOKINE RECEPTOR ANTAGONISTS | ASTRAZENECA AB (SE) | 2005-12-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080039499-A1 | Chemical Compounds | CCR1, CCL11, CXCR1 | GRM6 2270/4885ADORA1 327/4885COPS5 1789/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.