Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Trifluoroacetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL27936576 | 0.92 | — | — | |
| Trifluoroacetic Acid SCHEMBL7814389 | 0.91 | ALDH1A1 (0.44) | — | |
| Trifluoroacetic Acid SCHEMBL30657022 | 0.91 | — | — | |
| Trifluoroacetic Acid SCHEMBL2484766 | 0.91 | ALDH1A1 (0.44) | — | |
| Trifluoroacetic Acid SCHEMBL474 | 0.91 | — | — | |
| Trifluoroacetic Acid SCHEMBL4598430 | 0.91 | — | — | |
| Trifluoroacetic Acid SCHEMBL5299212 | 0.88 | ALDH1A1 (0.38) | — | |
| Trifluoroacetic Acid SCHEMBL25297651 | 0.87 | ALDH1A1 (0.42) | — | |
| Trifluoroacetic Acid SCHEMBL20571142 | 0.87 | — | — | |
| Trifluoroacetic Acid SCHEMBL641948 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113135966-B | Bicyclic derivatives of heterocyclic glucoside and preparation method and application thereof | 华润双鹤药业股份有限公司 | 2022-12-16 | — | — | CN | claimed |
| CN-113135966-A | Bicyclic derivatives of heterocyclic glucoside and preparation method and application thereof | 华润双鹤药业股份有限公司 | 2021-07-20 | — | — | CN | claimed |
| CN-113004157-A | Preparation method of ambroxol hydrochloride | 康普药业股份有限公司 | 2021-06-22 | — | — | CN | claimed |
| CN-112759623-A | Synthetic method of deoxycholic acid | 中山百灵生物技术股份有限公司 | 2021-05-07 | — | — | CN | claimed |
| US-9765044-B2 | Synthesis of novel ionic liquids from lignin-derived compounds | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-09-19 | — | — | US | claimed |
| US-20160031843-A1 | SYNTHESIS OF NOVEL IONIC LIQUIDS FROM LIGNIN-DERIVED COMPOUNDS | UNITED STATES DEPARTMENT OF ENERGY | 2016-02-04 | — | — | US | claimed |
| CN-105061230-A | Method for preparing dapoxetine hydrochloride | KAMP PHARMACEUTICALS CO LTD | 2015-11-18 | — | — | CN | claimed |
| CN-102702196-B | Method for synthesizing 3-methyl-7-diazaindene | NANJING YAOSHI PHARMACEUTICAL RES DEV CO LTD | 2015-01-14 | — | — | CN | claimed |
| WO-2014172042-A1 | SYNTHESIS OF NOVEL IONIC LIQUIDS FROM LIGNIN-DERIVED COMPOUNDS | SANDIA CORPORATION (US) | 2014-10-23 | — | — | WO | claimed |
| CN-103304466-A | Synthetic method of 3-alkyl-substituted indole compound | CHIMICA LAB CO LTD | 2013-09-18 | — | — | CN | claimed |
| CN-102249937-A | Preparation method of 1-(S)-4, 5-dimethyamino-1-methylaminomethyl-benzocyclobutane | SHANGHAI JINGXIN BIOLOG MEDICAL CO LTD | 2011-11-23 | — | — | CN | claimed |
| CN-102086202-A | Method for quickly preparing cis-octahydropyrrolo[3,2-b]pyrrole | WUXI APP INC | 2011-06-08 | — | — | CN | claimed |
| CN-113004157-A | Preparation method of ambroxol hydrochloride | 康普药业股份有限公司 | 2021-06-22 | — | — | CN | disclosed |
| CN-112759623-A | Synthetic method of deoxycholic acid | 中山百灵生物技术股份有限公司 | 2021-05-07 | — | — | CN | disclosed |
| CN-112759623-A | Synthetic method of deoxycholic acid | 中山百灵生物技术股份有限公司 | 2021-05-07 | — | — | CN | disclosed |
| CN-110551055-B | Preparation method of 3- (4-chlorobutyl) -5-cyanoindole | 新发药业有限公司 | 2021-01-22 | — | — | CN | disclosed |
| US-20020055505-A1 | SULTAM AND SULTONE DERIVED OXAZOLIDINONES | ANDERSON DAVID JOHN (US) | 2002-05-09 | — | — | US | disclosed |
| US-6348459-B1 | DRUGS AND ANTIBIOTIC AGENTS. | PHARMACIA AND UPJOHN COMPANY | 2002-02-19 | — | — | US | disclosed |
| WO-2001032657-A1 | ANTIBIOTIC SULTAM AND SULTONE DERIVED OXAZOLIDINONES | PHARMACIA & UPJOHN COMPANY (US) | 2001-05-10 | — | — | WO | disclosed |
| US-4935505-A | NUCLEOSIDES; ADENOSINE DEAMINASE INHIBITORS | TOWNSEND LEROY B (US) | 1990-06-19 | — | — | US | disclosed |