Phosphoric Acid

Phosphoric Acid

SCHEMBL28113088

Cn1ccc(N)nc1=O.O=P(O)(O)O

nearest known ligand 0.43

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FGFR1 known ✓ P11362 4/20 0.43
SLC22A6 Q4U2R8 1/20 0.42
LMNA P02545 3/20 0.36
THRB P10828 1/20 0.36
MTOR P42345 1/20 0.36
MDM2 Q00987 1/20 0.36
NCOA1 Q15788 1/20 0.36
NCOA3 Q9Y6Q9 1/20 0.36
PIK3CB P42338 1/20 0.36
PDE3A Q14432 3/20 0.35
CACNA1F O60840 2/20 0.35
ALB P02768 2/20 0.35
MAPT P10636 2/20 0.35
CACNA1D Q01668 2/20 0.35
CACNA1S Q13698 2/20 0.35
CACNA1C Q13936 2/20 0.35
NT5E P21589 1/20 0.34
POLA1 P09884 1/20 0.34
PDE4D Q08499 1/20 0.34
SLC29A1 Q99808 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL7818662 1.00 FGFR1 (0.43) FGFR1SLC22A6LMNATHRBMTOR
SCHEMBL27952255 0.90 PIK3CB (0.41) FGFR1SLC22A6LMNATHRBMTOR
SCHEMBL19929 0.90
Hydrochloric Acid SCHEMBL6853659 0.88 PIK3CB (0.40) FGFR1SLC22A6LMNATHRBMTOR
Sulfurous Acid SCHEMBL5695173 0.85 LMNA (0.36) FGFR1SLC22A6LMNATHRBMTOR
Cytosine SCHEMBL1673111 0.76 BRD4 (0.40) LMNATHRBMTORMDM2NCOA1
Phosphoric Acid SCHEMBL27689268 0.75 FGFR1 (0.57) FGFR1SLC22A6LMNATHRBMTOR
SCHEMBL1629582 0.71 FGFR1 (0.44) FGFR1SLC22A6LMNATHRBMTOR
SCHEMBL23128404 0.70
SCHEMBL48395 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106232834-A Sample preparation methods 牛津纳米孔技术公司 2016-12-14 CN disclosed