SCHEMBL2811323

SCHEMBL2811323

CC/C(=C\Oc1ccc(C)cc1)C(=O)O

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.42
LMNA P02545 2/20 0.40
MAOB P27338 2/20 0.37
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
FFAR1 O14842 1/20 0.36
MAPT P10636 1/20 0.36
HPGD P15428 1/20 0.36
PPARA Q07869 2/20 0.35
TRPM8 Q7Z2W7 1/20 0.35
ALDH1A1 P00352 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
GAA P10253 1/20 0.35
TP53 P04637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2811324 1.00 L3MBTL1 (0.42) L3MBTL1LMNAMAOBMEN1KMT2A
SCHEMBL2808659 0.86 CA1 (0.44)
SCHEMBL2808660 0.86 CA1 (0.44)
SCHEMBL2807242 0.86 RECQL (0.39) L3MBTL1LMNAMEN1KMT2AMAPT
SCHEMBL691461 0.86 RECQL (0.39) L3MBTL1LMNAMEN1KMT2AMAPT
SCHEMBL28065496 0.83 ALDH1A1 (0.43) LMNAKMT2AMAPTHPGDALDH1A1
SCHEMBL2811892 0.83 MAPT (0.41) L3MBTL1LMNAMAOBMEN1KMT2A
SCHEMBL2811889 0.83 MAPT (0.41) L3MBTL1LMNAMAOBMEN1KMT2A
SCHEMBL2813061 0.81 LMNA (0.46) L3MBTL1LMNAMEN1KMT2AHPGD
SCHEMBL2813058 0.81 LMNA (0.46) L3MBTL1LMNAMEN1KMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8278473-B2 Alpha, beta-unsaturated imidate compound and pesticidal composition containing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-02 US disclosed
US-20100240729-A1 ALPHA, BETA-UNSATURATED IMIDATE COMPOUND AND PESTICIDAL COMPOSITION CONTAINING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-09-23 US disclosed
WO-2009064031-A1 ALPHA, BETA-UNSATURATED IMIDATE COMPOUND AND PESTICIDAL COMPOSITION CONTAINING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-05-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100240729-A1 ALPHA, BETA-UNSATURATED IMIDATE COMPOUND AND PESTICIDAL COMPOSITION CONTAINING THE SAME OXER1, CBR1, DEGS1 L3MBTL1 307/4885LMNA 2201/4885MAOB 1038/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.