Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | NEK2 | P51955 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28113312 | 0.88 | TDP1 (0.44) | ALDH1A1KDM4EHPGDHSD17B10NR1H4 | |
| SCHEMBL27487116 | 0.78 | CFTR (0.41) | ALDH1A1KDM4EHPGDHSD17B10TSHR | |
| SCHEMBL10519686 | 0.78 | ALDH1A1 (0.59) | ALDH1A1PPARGPPARAKDM4EHPGD | |
| SCHEMBL26033050 | 0.76 | ALDH1A1 (0.53) | ALDH1A1PPARGPPARAKDM4EHPGD | |
| SCHEMBL4689119 | 0.75 | MEN1 (0.46) | ALDH1A1NR1H4TSHRMAPTMEN1 | |
| SCHEMBL106530 | 0.75 | ALDH1A1 (0.59) | ALDH1A1PPARGPPARAKDM4EHPGD | |
| SCHEMBL27876225 | 0.73 | KIF11 (0.45) | NR1H4MEN1KMT2ARAB9A | |
| SCHEMBL422034 | 0.73 | ALDH1A1 (0.71) | ALDH1A1PPARGPPARAKDM4EHPGD | |
| SCHEMBL17908094 | 0.73 | ALDH1A1 (0.57) | ALDH1A1PPARGPPARAKDM4EHPGD | |
| SCHEMBL18043813 | 0.73 | KDM4E (0.42) | ALDH1A1KDM4EHPGDHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110141570-A | Medical compounds | 西雅图遗传学公司 | 2019-08-20 | — | — | CN | disclosed |
| CN-110143950-A | Medical compounds | 西雅图遗传学公司 | 2019-08-20 | — | — | CN | disclosed |
| CN-106170288-B | Pharmaceutical compounds | 西雅图遗传学公司 | 2019-07-19 | — | — | CN | disclosed |
| CN-106170288-A | Pharmaceutical compounds | 卡斯卡迪安疗法公司 | 2016-11-30 | — | — | CN | disclosed |