Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 3/20 | 0.33 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 7/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 12/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27908446 | 0.85 | SLC6A2 (0.33) | RIPK1IDO1NR3C2NR3C1 | |
| SCHEMBL19413082 | 0.80 | RIPK1 (0.41) | RIPK1IDO1NR3C2NR3C1 | |
| SCHEMBL28113469 | 0.77 | CHRNB2 (0.35) | — | |
| SCHEMBL23964558 | 0.77 | NR3C1 (0.43) | RIPK1NR3C2NR3C1 | |
| SCHEMBL17552743 | 0.76 | RIPK1 (0.41) | RIPK1IDO1NR3C2KDM4E | |
| SCHEMBL27409142 | 0.74 | IDO1 (0.41) | RIPK1IDO1NR3C2NR3C1 | |
| SCHEMBL17378840 | 0.73 | CA3 (0.43) | RIPK1NR3C2NR3C1KDM4E | |
| SCHEMBL19354831 | 0.73 | NR3C1 (0.36) | RIPK1NR3C2NR3C1 | |
| SCHEMBL22023841 | 0.73 | NPSR1 (0.47) | NR3C2NR3C1 | |
| SCHEMBL22043372 | 0.69 | AR (0.40) | NR3C2NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102947319-B | Method and tertiary phosphine for phosphine oxides is reduced into corresponding tertiary phosphine in the presence of a catalyst is used for reducing in the presence of a catalyst the purposes of phosphine oxides | 克罗马福拉公司 | 2016-11-09 | — | — | CN | disclosed |