Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PTGES | O14684 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | MIF | P14174 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28114132 | 0.90 | L3MBTL1 (0.46) | L3MBTL1SMN1; SMN2HTTRAB9AMAPT | |
| SCHEMBL15552338 | 0.84 | PDE7A (0.41) | L3MBTL1PTGESDHODH | |
| SCHEMBL15553391 | 0.84 | PDE7A (0.38) | L3MBTL1MEN1KMT2APTGESP2RX7 | |
| SCHEMBL15552129 | 0.81 | L3MBTL1 (0.38) | L3MBTL1MEN1KMT2APTGESALDH1A1 | |
| SCHEMBL15552246 | 0.81 | RORC (0.42) | L3MBTL1PTGESSRCAURKBSRPK1 | |
| SCHEMBL17147573 | 0.81 | PTGES (0.45) | MEN1KMT2APTGESALDH1A1NPBWR1 | |
| SCHEMBL15551822 | 0.81 | LMNA (0.41) | L3MBTL1MAPTPTGESALDH1A1DHODH | |
| SCHEMBL15560879 | 0.81 | LMNA (0.39) | L3MBTL1SMN1; SMN2RAB9AMAPTMEN1 | |
| SCHEMBL15552633 | 0.81 | DHODH (0.43) | L3MBTL1MEN1KMT2AALDH1A1MAPK14 | |
| SCHEMBL15600557 | 0.79 | PDE7A (0.37) | L3MBTL1PTGESDHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104487433-B | Triazolone compounds as mPGES-1 inhibitors | 格兰马克药品股份有限公司 | 2016-12-07 | — | — | CN | disclosed |