Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | BRD4 | O60885 | 1/20 | 0.56 |
| ▸ | BRD2 | P25440 | 1/20 | 0.56 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | NSD2 | O96028 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29451363 | 0.86 | SMN1; SMN2 (0.52) | POLBBRD4BRD2BRD3SMN1; SMN2 | |
| SCHEMBL1032718 | 0.82 | KDM4E (0.60) | POLBBRD4BRD2BRD3SMN1; SMN2 | |
| SCHEMBL19931427 | 0.82 | ALDH1A1 (0.74) | BRD4BRD2BRD3SMN1; SMN2ALDH1A1 | |
| SCHEMBL407668 | 0.81 | CA12 (0.61) | POLBBRD4BRD2BRD3ALDH1A1 | |
| SCHEMBL4616633 | 0.80 | SFRP1 (0.76) | POLBBRD4BRD2BRD3SMN1; SMN2 | |
| SCHEMBL29451386 | 0.80 | MEN1 (0.51) | POLBSMN1; SMN2HTTALDH1A1MEN1 | |
| SCHEMBL29451549 | 0.80 | MEN1 (0.72) | POLBALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL9320070 | 0.80 | BRD4 (0.51) | BRD4BRD2BRD3SMN1; SMN2HTT | |
| SCHEMBL29451527 | 0.78 | THRB (0.45) | POLBSMN1; SMN2HTTKDM4EALDH1A1 | |
| SCHEMBL22433208 | 0.77 | CA12 (0.58) | POLBBRD4BRD2BRD3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106146358-B | Method for synthesizing amino- (N-alkyl) benzene sulfonamide | 南京理工大学 | 2018-01-23 | — | — | CN | disclosed |
| CN-106146358-A | Method for synthesizing amino- (N-alkyl) benzene sulfonamide | 南京理工大学 | 2016-11-23 | — | — | CN | disclosed |