Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.73 |
| ▸ | CA9 | Q16790 | 3/20 | 0.73 |
| ▸ | CA1 | P00915 | 2/20 | 0.73 |
| ▸ | CA2 | P00918 | 2/20 | 0.73 |
| ▸ | CA4 | P22748 | 1/20 | 0.73 |
| ▸ | CA6 | P23280 | 1/20 | 0.73 |
| ▸ | CA5A | P35218 | 1/20 | 0.73 |
| ▸ | CA7 | P43166 | 1/20 | 0.73 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.73 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.71 |
| ▸ | ATM | Q13315 | 1/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.68 |
| ▸ | LMNA | P02545 | 4/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | CNR2 | P34972 | 1/20 | 0.64 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25547142 | 0.91 | CA12 (0.83) | CA12CA9CYP1A2CYP3A4ATM | |
| SCHEMBL3789773 | 0.85 | CA2 (1.00) | CA12CA9CA1CA2CA4 | |
| SCHEMBL17827613 | 0.85 | CA12 (0.73) | CA12CA9CYP1A2CYP3A4ATM | |
| SCHEMBL28113716 | 0.84 | CA9 (0.69) | CA12CA9CA1CA2CA4 | |
| SCHEMBL6803886 | 0.84 | ALDH1A1 (0.84) | CA12CA9CA1CA2CA6 | |
| SCHEMBL28003780 | 0.84 | CA12 (0.67) | CA12CA9CYP1A2CYP3A4ATM | |
| SCHEMBL5960052 | 0.83 | CA12 (0.71) | CA12CA9CYP1A2CYP3A4ATM | |
| SCHEMBL5960116 | 0.83 | MEN1 (0.73) | CA12CA9CYP1A2CYP3A4ATM | |
| SCHEMBL3925035 | 0.83 | CA12 (0.71) | CA12CA9CYP1A2CYP3A4ATM | |
| SCHEMBL28836818 | 0.83 | CA1 (0.73) | CA12CA9CA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106146358-B | Method for synthesizing amino- (N-alkyl) benzene sulfonamide | 南京理工大学 | 2018-01-23 | — | — | CN | disclosed |
| CN-106146358-A | Method for synthesizing amino- (N-alkyl) benzene sulfonamide | 南京理工大学 | 2016-11-23 | — | — | CN | disclosed |