Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 15/20 | 1.00 |
| ▸ | CA1 | P00915 | 14/20 | 1.00 |
| ▸ | CA9 | Q16790 | 11/20 | 1.00 |
| ▸ | CA12 | O43570 | 7/20 | 1.00 |
| ▸ | CA6 | P23280 | 3/20 | 1.00 |
| ▸ | CA5A | P35218 | 3/20 | 1.00 |
| ▸ | CA7 | P43166 | 3/20 | 1.00 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 1.00 |
| ▸ | CA4 | P22748 | 2/20 | 1.00 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | AGO2 | Q9UKV8 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28113725 | 0.85 | CA12 (0.73) | CA2CA1CA9CA12CA6 | |
| SCHEMBL28836818 | 0.85 | CA1 (0.73) | CA2CA1CA9CA12CA6 | |
| SCHEMBL28113182 | 0.85 | CA1 (0.73) | CA2CA1CA9CA12CA6 | |
| SCHEMBL151655 | 0.84 | KEAP1 (0.76) | CA2CA1CA9CA12CA6 | |
| SCHEMBL13030968 | 0.83 | CA1 (1.00) | CA2CA1CA9CA12CA6 | |
| SCHEMBL28113716 | 0.82 | CA9 (0.69) | CA2CA1CA9CA12CA6 | |
| SCHEMBL7663045 | 0.81 | SMN1; SMN2 (0.71) | CA2CA1CA9CA12CA6 | |
| SCHEMBL14196598 | 0.81 | CA2 (0.68) | CA2CA1CA9CA12CA6 | |
| SCHEMBL4915517 | 0.81 | ALDH1A1 (0.76) | CA2CA1CA9CA12CA6 | |
| SCHEMBL1685120 | 0.81 | CA2 (0.68) | CA2CA1CA9CA12CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010061185-A2 | THERAPEUTIC TARGET | UNION LIFE SCIENCES LTD (GB) | 2010-06-03 | — | — | WO | claimed |
| EP-2594265-B1 | Ca ix-specific inhibitors | INST VIROLOGY (SK) | 2015-10-28 | — | — | EP | disclosed |
| EP-2594265-A1 | Ca ix-specific inhibitors | INSTITUTE OF VIROLOGY (SK) | 2013-05-22 | — | — | EP | disclosed |
| US-7829065-B2 | CA IX-specific inhibitors | INSTITUTE OF VIROLOGY OF THE SLOVAK ACADEMY OF SCIENCES (SK) | 2010-11-09 | — | — | US | disclosed |
| WO-2010086177-A1 | SULFAMOYL- PHENYL-UREIDO BENZAMIDINE-DERIVATIVES AS ANTIMALARIAL AGENTS | 4SC AG (DE) | 2010-08-05 | — | — | WO | disclosed |
| WO-2010061185-A2 | THERAPEUTIC TARGET | UNION LIFE SCIENCES LTD (GB) | 2010-06-03 | — | — | WO | disclosed |
| US-7550424-B2 | CA IX-specific inhibitors | INSTITUTE OF VIROLOGY SLOVAK ACADEMY OF SCIENCES (SK) | 2009-06-23 | — | — | US | disclosed |
| US-20080095707-A1 | CA IX-SPECIFIC INHIBITORS | INSTITUTE OF VIROLOGY SLOVAK ACADEMY OF SCIENCES (SK) | 2008-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080095707-A1 | CA IX-SPECIFIC INHIBITORS | CA9, CA6, CA14 | CA2 5/4885CA1 4/4885CA9 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.