Fluorene

Fluorene

SCHEMBL28113829

Oc1cccc2ccccc12.Oc1cccc2ccccc12.c1ccc2c(c1)Cc1ccccc1-2

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.65
MAOA P21397 1/20 0.42
MAPT P10636 4/20 0.41
TSHR P16473 3/20 0.41
HSD17B10 Q99714 3/20 0.41
ALDH1A1 P00352 2/20 0.41
MEN1 O00255 2/20 0.41
CYP3A4 P08684 2/20 0.41
KMT2A Q03164 2/20 0.41
THRB P10828 2/20 0.41
ALOX15 P16050 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
USP2 O75604 1/20 0.41
HPN P05981 1/20 0.41
ALOX5 P09917 1/20 0.41
PTGS1 P23219 1/20 0.41
PDE4A P27815 1/20 0.41
KDR P35968 1/20 0.41
SIRT5 Q9NXA8 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluorene SCHEMBL870544 1.00 CYP1A2 (0.65) CYP1A2MAOAMAPTTSHRHSD17B10
Fluorene SCHEMBL28714196 0.84 MAOA (0.48) MAOAMAPTTSHRHSD17B10ALDH1A1
1-Naphthol SCHEMBL17456245 0.82 CYP1A2 (0.47) CYP1A2PNMTNPC1RAB9ACA1
Phenanthrene SCHEMBL21219119 0.81 TSHR (0.57) CYP1A2MAOAMAPTTSHRHSD17B10
1-Naphthol SCHEMBL8748998 0.81 CYP1A2 (0.81) CYP1A2MAPTTSHRHSD17B10ALDH1A1
Fluorene SCHEMBL28466769 0.81 MAOA (0.54) CYP1A2MAOAMAPTTSHRHSD17B10
1-Naphthol SCHEMBL10486461 0.81 CYP1A2 (1.00) CYP1A2MAPTTSHRHSD17B10ALDH1A1
1-Naphthol SCHEMBL29767730 0.81 CYP1A2 (1.00) CYP1A2MAPTTSHRHSD17B10ALDH1A1
1-Naphthol SCHEMBL273260 0.81 CYP1A2 (1.00) CYP1A2MAPTTSHRHSD17B10ALDH1A1
1-Naphthol SCHEMBL3416 0.81 CYP1A2 (1.00) CYP1A2MAPTTSHRHSD17B10ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111812942-A Photosensitive resin composition, cured film and display device 日铁化学材料株式会社 2020-10-23 CN disclosed
CN-106170737-B Antireflective coating compositions and its method AZ电子材料卢森堡有限公司 2019-08-06 CN disclosed
CN-109976090-A Thermosetting composition, cured film and display device 日铁化学材料株式会社 2019-07-05 CN disclosed
CN-109715698-A Alkali soluble resins and alkali soluble type radiation sensitive resin composition containing unsaturated group 长濑化成株式会社 2019-05-03 CN disclosed
CN-106170737-A Antireflective coating compositions and method thereof AZ电子材料卢森堡有限公司 2016-11-30 CN disclosed