SCHEMBL28113909

SCHEMBL28113909

NC(=O)Cn1cc(N)c(=O)[nH]c1=O

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.40
LMNA P02545 1/20 0.40
GRIA1 P42261 4/20 0.39
GRIA2 P42262 4/20 0.39
GRIA4 P48058 4/20 0.39
GRIK5 Q16478 4/20 0.39
CYP1A2 P05177 2/20 0.39
BLM P54132 1/20 0.39
HSD17B10 Q99714 1/20 0.39
KDM4E B2RXH2 1/20 0.39
GRIA3 P42263 1/20 0.39
MAPT P10636 1/20 0.38
CYP2C9 P11712 1/20 0.38
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA9 Q16790 1/20 0.36
HTT P42858 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL452185 0.81 MAPK1 (0.53)
SCHEMBL23211184 0.79 KMT2A (0.64) KMT2ALMNACYP1A2MAPTCYP2C9
SCHEMBL13384449 0.77 GRIA1 (0.41) KMT2ALMNAGRIA1GRIA2GRIA4
SCHEMBL8014516 0.76 KMT2A (0.40) KMT2ALMNAGRIA1GRIA2GRIA4
SCHEMBL20359507 0.73 CYP1A2 (0.45) KMT2ALMNACYP1A2BLMHSD17B10
SCHEMBL28985696 0.71 TK1 (0.37) KMT2A
SCHEMBL10458521 0.71 UPP1 (0.57) BLMHSD17B10
SCHEMBL11710759 0.69 ALDH1A1 (0.58) KMT2ALMNAKDM4ECA1CA2
SCHEMBL23211195 0.66 TYMP (0.48) KMT2ACYP1A2MAPTCYP2C9HTT
SCHEMBL23211180 0.66 TYMP (0.48) KMT2ACYP1A2MAPTCYP2C9HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115960480-B Light response self-repairing material containing thymine derivative and application thereof 合肥工业大学 2023-09-12 CN disclosed
CN-115960480-A Light response self-repairing material containing thymine derivative and application thereof 合肥工业大学 2023-04-14 CN disclosed
CN-106170553-A Modified nucleic acid molecules and uses thereof 现代治疗公司 2016-11-30 CN disclosed