Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.33 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.33 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.33 |
| ▸ | GRIK5 | Q16478 | 2/20 | 0.33 |
| ▸ | MPO | P05164 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL452185 | 0.82 | MAPK1 (0.53) | MAPK1 | |
| SCHEMBL28985696 | 0.80 | TK1 (0.37) | KMT2AMAPK1 | |
| SCHEMBL28113909 | 0.76 | KMT2A (0.40) | KMT2AMAPTCYP2C9LMNAKDM4E | |
| SCHEMBL13384449 | 0.75 | GRIA1 (0.41) | KMT2AMAPTCYP2C9LMNAKDM4E | |
| SCHEMBL11710759 | 0.70 | ALDH1A1 (0.58) | KMT2ALMNAKDM4EMEN1 | |
| SCHEMBL27033920 | 0.67 | ALDH1A1 (0.45) | KMT2AMAPTPGRLMNAKDM4E | |
| SCHEMBL17013819 | 0.67 | MAPK1 (0.56) | MAPK1 | |
| SCHEMBL10884744 | 0.67 | LPO (0.42) | KMT2AMAPTLMNAKDM4ECYP1A2 | |
| SCHEMBL8011916 | 0.67 | TRPA1 (0.40) | MAPTLMNAKDM4EHSD17B10 | |
| Formic Acid SCHEMBL30635208 | 0.66 | ALDH1A1 (0.52) | KMT2ALMNAKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6034083-A | AGRICULTURAL INSECTICIDE | NOVARTIS CORP. (US) | 2000-03-07 | — | — | US | disclosed |
| US-5783704-A | INSECTICIDES; FOR AGRICULTURE PRODUCTS | NOVARTIS CORPORATION (US) | 1998-07-21 | — | — | US | disclosed |
| EP-0737191-A1 | PYRIDINE DERIVATIVES AS PESTICIDES | Novartis AG (CH) | 1996-10-16 | — | — | EP | disclosed |
| WO-1995018123-A1 | PYRIDINE DERIVATIVES AS PESTICIDES | CIBA-GEIGY AG (CH) | 1995-07-06 | — | — | WO | disclosed |