SCHEMBL28985696

SCHEMBL28985696

Cc1cn(CC(N)=O)c(=O)[nH]c1=S

nearest known ligand 0.44

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TK1 P04183 5/20 0.37
KMT2A Q03164 1/20 0.37
MAPK1 P28482 1/20 0.36
HPGD P15428 1/20 0.36
TYMP P19971 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28985700 0.84 LMNA (0.42) TK1KMT2AMAPK1TYMP
SCHEMBL452185 0.83 MAPK1 (0.53) TK1MAPK1HPGDTYMP
SCHEMBL8014516 0.80 KMT2A (0.40) KMT2AMAPK1
SCHEMBL11723021 0.78 SMN1; SMN2 (0.44) TK1MAPK1HPGDTYMP
SCHEMBL7546901 0.75 TK1 (0.42) TK1KMT2AMAPK1HPGDTYMP
SCHEMBL7549198 0.73 TYMP (0.43) TK1MAPK1HPGDTYMP
SCHEMBL7554990 0.72 TK1 (0.47) TK1KMT2AMAPK1HPGDTYMP
SCHEMBL28113909 0.71 KMT2A (0.40) KMT2A
SCHEMBL13384449 0.70 GRIA1 (0.41) KMT2ATYMP
SCHEMBL17013819 0.69 MAPK1 (0.56) TK1MAPK1HPGDTYMP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115960480-B Light response self-repairing material containing thymine derivative and application thereof 合肥工业大学 2023-09-12 CN claimed
CN-115960480-A Light response self-repairing material containing thymine derivative and application thereof 合肥工业大学 2023-04-14 CN claimed
CN-115960480-B Light response self-repairing material containing thymine derivative and application thereof 合肥工业大学 2023-09-12 CN disclosed
CN-115960480-A Light response self-repairing material containing thymine derivative and application thereof 合肥工业大学 2023-04-14 CN disclosed