Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 4/20 | 0.74 |
| ▸ | CHRM2 known ✓ | P08172 | 2/20 | 0.74 |
| ▸ | CHRM1 known ✓ | P11229 | 2/20 | 0.74 |
| ▸ | SLC6A2 known ✓ | P23975 | 2/20 | 0.74 |
| ▸ | SLC6A3 known ✓ | Q01959 | 2/20 | 0.74 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.78 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.78 |
| ▸ | MEN1 | O00255 | 1/20 | 0.78 |
| ▸ | MAPT | P10636 | 1/20 | 0.78 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.78 |
| ▸ | CASP2 | P42575 | 1/20 | 0.78 |
| ▸ | RAD52 | P43351 | 3/20 | 0.75 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.75 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.75 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.74 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.74 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.74 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.74 |
| ▸ | ESR1 | P03372 | 1/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL222581 | 0.97 | KMT2A (0.82) | KMT2ASMN1; SMN2MEN1MAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL28055230 | 0.95 | KMT2A (0.78) | KMT2ASMN1; SMN2MEN1MAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL28142757 | 0.95 | KMT2A (0.78) | KMT2ASMN1; SMN2MEN1MAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL28020632 | 0.95 | KMT2A (0.78) | KMT2ASMN1; SMN2MEN1MAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL621908 | 0.95 | KMT2A (0.78) | KMT2ASMN1; SMN2MEN1MAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL5271957 | 0.95 | KMT2A (0.78) | KMT2ASMN1; SMN2MEN1MAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL4005754 | 0.95 | KMT2A (0.78) | KMT2ASMN1; SMN2MEN1MAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL28697633 | 0.95 | KMT2A (0.78) | KMT2ASMN1; SMN2MEN1MAPTMAPK1 | |
| SCHEMBL34882 | 0.95 | ACHE (0.81) | KMT2ASMN1; SMN2MEN1MAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL7188577 | 0.93 | KMT2A (0.75) | KMT2ASMN1; SMN2MEN1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106849390-A | A kind of air conditioning pump with permagnetic synchronous motor | 浙江贝德泵业有限公司 | 2017-06-13 | — | — | CN | claimed |
| CN-105368405-B | The new application of magnetic ionic liquids | 昆明理工大学 | 2019-01-04 | — | — | CN | disclosed |
| CN-106849390-A | A kind of air conditioning pump with permagnetic synchronous motor | 浙江贝德泵业有限公司 | 2017-06-13 | — | — | CN | disclosed |
| CN-105238434-B | The method orienting regulation and control liquid-phase catalysis biomass through pyrolysis using magnetic ionic liquids | 昆明理工大学 | 2017-03-08 | — | — | CN | disclosed |
| CN-205227828-U | Utilize device of magnetism ionic liquid electroproduction hotwork for heating medium | UNIV KUNMING SCIENCE & TECHNOLOGY | 2016-05-11 | — | — | CN | disclosed |
| CN-105368405-A | Novel application of magnetic ionic liquid | UNIV KUNMING SCIENCE & TECHNOLOGY | 2016-03-02 | — | — | CN | disclosed |
| CN-105238434-A | Method for directional adjustment and control of liquid phase catalysis biomass thermal cracking by means of magnetic ion liquid | UNIV KUNMING SCIENCE & TECHNOLOGY | 2016-01-13 | — | — | CN | disclosed |