Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 4/20 | 0.74 |
| ▸ | CHRM2 known ✓ | P08172 | 2/20 | 0.74 |
| ▸ | CHRM1 known ✓ | P11229 | 2/20 | 0.74 |
| ▸ | SLC6A2 known ✓ | P23975 | 2/20 | 0.74 |
| ▸ | SLC6A3 known ✓ | Q01959 | 2/20 | 0.74 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.78 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.78 |
| ▸ | MEN1 | O00255 | 1/20 | 0.78 |
| ▸ | MAPT | P10636 | 1/20 | 0.78 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.78 |
| ▸ | CASP2 | P42575 | 1/20 | 0.78 |
| ▸ | RAD52 | P43351 | 3/20 | 0.75 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.75 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.75 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.74 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.74 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.74 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.74 |
| ▸ | ESR1 | P03372 | 1/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL222581 | 0.97 | KMT2A (0.82) | KMT2ASMN1; SMN2MEN1MAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL28020632 | 0.95 | KMT2A (0.78) | KMT2ASMN1; SMN2MEN1MAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL28114079 | 0.95 | KMT2A (0.78) | KMT2ASMN1; SMN2MEN1MAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL28055230 | 0.95 | KMT2A (0.78) | KMT2ASMN1; SMN2MEN1MAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL4005754 | 0.95 | KMT2A (0.78) | KMT2ASMN1; SMN2MEN1MAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL5271957 | 0.95 | KMT2A (0.78) | KMT2ASMN1; SMN2MEN1MAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL28697633 | 0.95 | KMT2A (0.78) | KMT2ASMN1; SMN2MEN1MAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL28142757 | 0.95 | KMT2A (0.78) | KMT2ASMN1; SMN2MEN1MAPTMAPK1 | |
| SCHEMBL34882 | 0.95 | ACHE (0.81) | KMT2ASMN1; SMN2MEN1MAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL7188577 | 0.93 | KMT2A (0.75) | KMT2ASMN1; SMN2MEN1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110269263-A1 | METHOD FOR IMPLANTING IMPURITIES INTO A SUBSTRATE AND METHOD FOR MANUFACTURING A SOLAR CELL USING THE SAME | SAMSUNG DISPLAY CO., LTD. (KR) | 2011-11-03 | — | — | US | claimed |
| US-7605283-B2 | Process for preparing Si-H-containing silanes | WACKER CHEMIE AG (DE) | 2009-10-20 | — | — | US | claimed |
| US-6288281-B1 | REACTION OF CARBON MONOXIDE WITH HYDROCARBONS FOR OXYGENATED SATURATED HYDROCARBONS | UOP LLC | 2001-09-11 | — | — | US | claimed |
| US-4554383-A | Process for producing p-tolualdehyde from toluene using an aluminum halide alkyl pyridinium halide `melt` catalyst | TEXACO INC. (US) | 1985-11-19 | — | — | US | claimed |
| US-20230304179-A1 | Reactor for Electrochemical Deposition | Fabric8Labs, Inc. (US) | 2023-09-28 | — | — | US | disclosed |
| US-11591705-B2 | Electrochemical layer deposition | Fabric8Labs, Inc. (US) | 2023-02-28 | — | — | US | disclosed |
| US-20210301414-A1 | ELECTROCHEMICAL LAYER DEPOSITION | Fabric8Labs, Inc. (US) | 2021-09-30 | — | — | US | disclosed |
| US-10975485-B2 | Electrochemical layer deposition by controllable anode array | Fabric8Labs, Inc. (US) | 2021-04-13 | — | — | US | disclosed |
| CN-112264095-A | Polymeric ionic liquid solid acid catalyst for catalyzing esterification reaction of pentaerythritol and oleic acid and preparation method thereof | 常州大学 | 2021-01-26 | — | — | CN | disclosed |
| US-10669635-B2 | Methods of coating substrates with composite coatings of diamond nanoparticles and metal | BAKER HUGHES, A GE COMPANY, LLC (US) | 2020-06-02 | — | — | US | disclosed |
| US-10465307-B2 | Apparatus for electrochemical additive manufacturing | Fabric8Labs, Inc. (US) | 2019-11-05 | — | — | US | disclosed |
| US-20190301034-A1 | ELECTROCHEMICAL LAYER DEPOSITION BY CONTROLLABLE ANODE ARRAY | Fabric8Labs, Inc. (US) | 2019-10-03 | — | — | US | disclosed |
| CN-102473903-A | Fiber electrode, fiber battery, method for manufacturing fiber battery, fiber electrode, and apparatus for manufacturing fiber battery | KAWASAKI HEAVY IND LTD | 2012-05-23 | — | — | CN | disclosed |
| US-20120040246-A1 | Fiber Electrode for Lithium Secondary Battery, Fabrication Method Therefor, and Lithium Secondary Battery Including Fiber Electrode | KAWASAKI JUKOGYO KABUSHIKI KAISHA (JP) | 2012-02-16 | — | — | US | disclosed |
| US-20110269263-A1 | METHOD FOR IMPLANTING IMPURITIES INTO A SUBSTRATE AND METHOD FOR MANUFACTURING A SOLAR CELL USING THE SAME | SAMSUNG DISPLAY CO., LTD. (KR) | 2011-11-03 | — | — | US | disclosed |
| US-7605283-B2 | Process for preparing Si-H-containing silanes | WACKER CHEMIE AG (DE) | 2009-10-20 | — | — | US | disclosed |
| US-20080319214-A1 | Process For Preparing Si-H-Containing Silanes | WACKER CHEMIE AG (DE) | 2008-12-25 | — | — | US | disclosed |
| US-6565820-B1 | Using fluidized bed; reducing nitrogen oxide emission | UNIVERSITY TECHNOLOGY CORPORATION | 2003-05-20 | — | — | US | disclosed |
| US-6406677-B1 | GROUP III-V COMPOUNDS AND PRECUSORS | ELTRON RESEARCH, INC. | 2002-06-18 | — | — | US | disclosed |
| US-4786567-A | All-vanadium redox battery | UNISEARCH LIMITED (AU) | 1988-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080319214-A1 | Process For Preparing Si-H-Containing Silanes | CBX4, HAX1, BRIX1 | ACHE 3864/4885CHRM2 3974/4885CHRM1 3335/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.