Hydrochloric Acid

Hydrochloric Acid

SCHEMBL4005754

CCCC[n+]1ccccc1.[Al+3].[Cl-].[Cl-].[Cl-].[Cl-]

nearest known ligand 0.78

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE known ✓ P22303 4/20 0.74
CHRM2 known ✓ P08172 2/20 0.74
CHRM1 known ✓ P11229 2/20 0.74
SLC6A2 known ✓ P23975 2/20 0.74
SLC6A3 known ✓ Q01959 2/20 0.74
CHRM3 known ✓ P20309 1/20 0.71
KMT2A Q03164 2/20 0.78
SMN1; SMN2 Q16637 2/20 0.78
MEN1 O00255 1/20 0.78
MAPT P10636 1/20 0.78
MAPK1 P28482 1/20 0.78
CASP2 P42575 1/20 0.78
RAD52 P43351 3/20 0.75
HSPD1 P10809 1/20 0.75
HSPE1 P61604 1/20 0.75
ADRA2A P08913 2/20 0.74
ADORA3 P0DMS8 2/20 0.74
SLC6A4 P31645 2/20 0.74
ABCB11 O95342 1/20 0.74
ESR1 P03372 1/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL222581 0.97 KMT2A (0.82) KMT2ASMN1; SMN2MEN1MAPTMAPK1
Hydrochloric Acid SCHEMBL28055230 0.95 KMT2A (0.78) KMT2ASMN1; SMN2MEN1MAPTMAPK1
Hydrochloric Acid SCHEMBL28114079 0.95 KMT2A (0.78) KMT2ASMN1; SMN2MEN1MAPTMAPK1
Hydrochloric Acid SCHEMBL4005759 0.95 ACHE (0.74) KMT2ASMN1; SMN2MEN1MAPTMAPK1
Hydrochloric Acid SCHEMBL621908 0.95 KMT2A (0.78) KMT2ASMN1; SMN2MEN1MAPTMAPK1
Hydrochloric Acid SCHEMBL5271957 0.95 KMT2A (0.78) KMT2ASMN1; SMN2MEN1MAPTMAPK1
Hydrochloric Acid SCHEMBL28697633 0.95 KMT2A (0.78) KMT2ASMN1; SMN2MEN1MAPTMAPK1
Hydrochloric Acid SCHEMBL28142757 0.95 KMT2A (0.78) KMT2ASMN1; SMN2MEN1MAPTMAPK1
Hydrochloric Acid SCHEMBL28020632 0.95 KMT2A (0.78) KMT2ASMN1; SMN2MEN1MAPTMAPK1
SCHEMBL34882 0.95 ACHE (0.81) KMT2ASMN1; SMN2MEN1MAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8598378-B2 Methods and compositions for extraction and transesterification of biomass components UNIVERSITY OF HAWAII (US) 2013-12-03 US claimed
WO-2009114830-A2 METHODS AND COMPOSITIONS FOR EXTRACTION AND TRANSESTERIFICATION OF BIOMASS COMPONENTS UNIVERSITY OF HAWAII (US) 2009-09-17 WO claimed
US-20090234146-A1 METHODS AND COMPOSITIONS FOR EXTRACTION AND TRANSESTERIFICATION OF BIOMASS COMPONENTS UNIVERSITY OF HAWAII (US) 2009-09-17 US claimed
CN-116075497-A Composite forms of tetraacetylethylene diamine 一星解决方案有限公司 2023-05-05 CN disclosed
CN-111732534-A Method for synthesizing 2-amino-5-chloropyridine under catalysis of microwave and Lewis acidic ionic liquid 山东金城柯瑞化学有限公司 2020-10-02 CN disclosed
CN-111187206-A Method for synthesizing 2-amino-5-bromopyridine under catalysis of microwave and ionic liquid 山东金城柯瑞化学有限公司 2020-05-22 CN disclosed
US-8598378-B2 Methods and compositions for extraction and transesterification of biomass components UNIVERSITY OF HAWAII (US) 2013-12-03 US disclosed
WO-2009114830-A2 METHODS AND COMPOSITIONS FOR EXTRACTION AND TRANSESTERIFICATION OF BIOMASS COMPONENTS UNIVERSITY OF HAWAII (US) 2009-09-17 WO disclosed
US-20090234146-A1 METHODS AND COMPOSITIONS FOR EXTRACTION AND TRANSESTERIFICATION OF BIOMASS COMPONENTS UNIVERSITY OF HAWAII (US) 2009-09-17 US disclosed
US-6565820-B1 Using fluidized bed; reducing nitrogen oxide emission UNIVERSITY TECHNOLOGY CORPORATION 2003-05-20 US disclosed
US-6406677-B1 GROUP III-V COMPOUNDS AND PRECUSORS ELTRON RESEARCH, INC. 2002-06-18 US disclosed
EP-0323520-B1 PROCESS FOR ELECTROPLATING METAL PLATE WITH ALUMINUM NISSHIN STEEL CO., LTD. (JP) 1992-11-11 EP disclosed
US-4966660-A USING BATH OF MELTED ALUMINUM BROMIDE, CHLORIDE OR IODIDE WITH N-ALKYLPYRIDINIUM HALIDE; PRETREATMENT, ACTIVATION NISSHIN STEEL CO., LTD. (JP) 1990-10-30 US disclosed
EP-0323520-A1 PROCESS FOR ELECTROPLATING METAL PLATE WITH ALUMINUM NISSHIN STEEL CO., LTD. (JP) 1989-07-12 EP disclosed