Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | PNMT | P11086 | 3/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | F11 | P03951 | 1/20 | 0.32 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28114141 | 0.83 | PNMT (0.45) | MAPTTDP1KDM4ENPC1POLB | |
| Tert-Butyl Formate SCHEMBL28114131 | 0.82 | TDP1 (0.38) | MAPTTDP1KDM4ENPC1POLB | |
| SCHEMBL16280178 | 0.82 | MAPT (0.50) | MAPTTDP1KDM4ENPC1POLB | |
| SCHEMBL27264472 | 0.82 | PNMT (0.43) | PNMTDPP4IDO1TAAR1ALDH1A1 | |
| SCHEMBL27556745 | 0.75 | LOXL2 (0.35) | MAPTTDP1KDM4ENPC1POLB | |
| SCHEMBL833283 | 0.75 | MAPT (0.55) | MAPTTDP1KDM4ENPC1POLB | |
| SCHEMBL29502263 | 0.75 | MAPT (0.55) | MAPTTDP1KDM4ENPC1POLB | |
| SCHEMBL28115527 | 0.74 | AR (0.38) | MAPTNPC1RAB9APNMTDPP4 | |
| Hydrochloric Acid SCHEMBL629175 | 0.73 | MAPT (0.53) | MAPTTDP1KDM4ENPC1POLB | |
| SCHEMBL42557 | 0.73 | PNMT (0.52) | MAPTTDP1POLBPNMTDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104487433-B | Triazolone compounds as mPGES-1 inhibitors | 格兰马克药品股份有限公司 | 2016-12-07 | — | — | CN | disclosed |