Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 3/20 | 0.38 |
| ▸ | PNMT | P11086 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | KCNJ5 | P48544 | 2/20 | 0.33 |
| ▸ | KCNJ3 | P48549 | 2/20 | 0.33 |
| ▸ | IL1B | P01584 | 1/20 | 0.33 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28009482 | 0.80 | MAPT (0.49) | ARMAPTMEN1KMT2AATM | |
| SCHEMBL18300960 | 0.76 | RAPGEF4 (0.40) | ARMAPTMEN1KMT2AATM | |
| SCHEMBL453843 | 0.76 | IL1B (0.43) | ARMAPTMEN1KMT2AATM | |
| SCHEMBL28114122 | 0.74 | MAPT (0.47) | PNMTMAPTMEN1KMT2AATM | |
| SCHEMBL27264472 | 0.73 | PNMT (0.43) | PNMTL3MBTL1CYP3A4ALDH1A1DPP4 | |
| SCHEMBL9189930 | 0.72 | IL1B (0.43) | ARMAPTMEN1KMT2AIL1B | |
| SCHEMBL10426372 | 0.70 | SMN1; SMN2 (0.44) | ARMEN1KMT2AIL1BNLRP3 | |
| SCHEMBL856434 | 0.69 | PNMT (0.43) | PNMTMAPTMEN1KMT2AATM | |
| SCHEMBL3290963 | 0.69 | SLC22A12 (0.47) | ARMAPT | |
| SCHEMBL28009497 | 0.69 | IL1B (0.36) | ARMAPTMEN1KMT2AIL1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106132928-A | Novel anil, medical composition and its use containing described derivant | 橘生药品工业株式会社 | 2016-11-16 | — | — | CN | disclosed |