SCHEMBL28114239

SCHEMBL28114239

O=c1c2ccccc2oc2ccc(-c3cccc(Br)c3)cc12

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRP O00591 4/20 0.58
GABRD O14764 4/20 0.58
GABRA1 P14867 4/20 0.58
GABRB1 P18505 4/20 0.58
GABRG2 P18507 4/20 0.58
GABRB3 P28472 4/20 0.58
GABRA5 P31644 4/20 0.58
GABRA3 P34903 4/20 0.58
GABRA2 P47869 4/20 0.58
GABRB2 P47870 4/20 0.58
GABRA4 P48169 4/20 0.58
GABRE P78334 4/20 0.58
GABRA6 Q16445 4/20 0.58
GABRG1 Q8N1C3 4/20 0.58
GABRG3 Q99928 4/20 0.58
GABRQ Q9UN88 4/20 0.58
CASP3 P42574 1/20 0.56
SENP7 Q9BQF6 1/20 0.56
SENP6 Q9GZR1 1/20 0.56
MAOA P21397 4/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28113869 0.91 GABRP (0.58) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL28367741 0.89 CASP3 (0.57) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL4572508 0.89 MAOA (0.64) CASP3SENP7SENP6MAOAKDM4E
SCHEMBL4572503 0.89 MAOA (0.64) CASP3SENP7SENP6MAOAKDM4E
SCHEMBL4572501 0.89 MAOA (0.64) CASP3SENP7SENP6MAOAKDM4E
SCHEMBL28113736 0.88 MAOA (0.58) CASP3SENP7SENP6MAOAKDM4E
SCHEMBL29655725 0.88 MAOA (0.58) CASP3SENP7SENP6MAOAKDM4E
SCHEMBL29655739 0.88 MAOA (0.58) CASP3SENP7SENP6MAOAKDM4E
SCHEMBL4572517 0.87 MAOA (0.62) CASP3SENP7SENP6MAOAKDM4E
SCHEMBL29632081 0.87 GABRP (0.56) GABRPGABRDGABRA1GABRB1GABRG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106467483-B Five-membered ring substituted compound with xanthone as core and application thereof 中节能万润股份有限公司 2020-10-30 CN disclosed
CN-106467550-B Dibenzo six-membered ring substituted compound with xanthone as core and application thereof 江苏三月光电科技有限公司 2020-03-27 CN disclosed
CN-107068910-B A kind of organic electroluminescence device of the compound containing xanthone and its application 中节能万润股份有限公司 2019-07-19 CN disclosed
CN-106220638-B A kind of compound and its application based on xanthone 中节能万润股份有限公司 2018-06-26 CN disclosed
CN-107068910-A A kind of organic electroluminescence device of compound containing xanthone and its application 中节能万润股份有限公司 2017-08-18 CN disclosed
CN-106467483-A A kind of five-membered ring substituted compound with xanthone as core and its application 江苏三月光电科技有限公司 2017-03-01 CN disclosed
CN-106467550-A A kind of dibenzo hexatomic ring substituted compound with xanthone as core and its application 江苏三月光电科技有限公司 2017-03-01 CN disclosed
CN-106220638-A A kind of compound based on xanthone and application thereof 中节能万润股份有限公司 2016-12-14 CN disclosed