SCHEMBL28113736

SCHEMBL28113736

O=c1c2ccccc2oc2ccc(-c3ccc(Br)cc3)cc12

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 5/20 0.58
CASP3 P42574 1/20 0.58
SENP7 Q9BQF6 1/20 0.58
SENP6 Q9GZR1 1/20 0.58
KDM4E B2RXH2 1/20 0.58
ALDH1A1 P00352 1/20 0.58
GLA P06280 1/20 0.58
CYP3A4 P08684 1/20 0.58
MAPT P10636 1/20 0.58
HPGD P15428 1/20 0.58
PGAM1 P18669 1/20 0.58
CASP1 P29466 1/20 0.58
CASP7 P55210 1/20 0.58
SMN1; SMN2 Q16637 1/20 0.58
HSD17B10 Q99714 1/20 0.58
TNKS O95271 1/20 0.56
TTR P02766 2/20 0.53
NPC1 O15118 5/20 0.51
RAB9A P51151 4/20 0.51
POLB P06746 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29655739 1.00 MAOA (0.58) MAOACASP3SENP7SENP6KDM4E
SCHEMBL29655725 1.00 MAOA (0.58) MAOACASP3SENP7SENP6KDM4E
SCHEMBL4572502 0.92 MAOA (0.69) MAOACASP3SENP7SENP6KDM4E
SCHEMBL28114240 0.90 MAOA (0.58) MAOACASP3SENP7SENP6KDM4E
SCHEMBL12608739 0.90 MAOA (0.72) MAOACASP3SENP7SENP6KDM4E
SCHEMBL28367741 0.89 CASP3 (0.57) MAOACASP3SENP7SENP6KDM4E
SCHEMBL6897957 0.88 MAOA (0.64) MAOACASP3SENP7SENP6KDM4E
SCHEMBL4572490 0.88 MAOA (0.69) MAOACASP3SENP7SENP6KDM4E
SCHEMBL28114239 0.88 GABRP (0.58) MAOACASP3SENP7SENP6KDM4E
SCHEMBL4572496 0.87 GABRP (0.59) CASP3SENP7SENP6CYP3A4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111484468-B Compound for preparing organic photoelectric device 烟台显华光电材料研究院有限公司 2023-09-22 CN disclosed
CN-111454263-B Thermally activated delayed fluorescence material, organic light emitting device, and display/illumination device 苏州大学 2023-05-02 CN disclosed
CN-111048670-B Organic electroluminescent device 烟台显华光电材料研究院有限公司 2022-05-20 CN disclosed
CN-111484468-A Compound for preparing organic photoelectric device 烟台显华光电材料研究院有限公司 2020-08-04 CN disclosed
CN-111454263-A Thermally activated delayed fluorescent material, organic light emitting device and display/lighting device 苏州大学 2020-07-28 CN disclosed
CN-111048670-A Organic electroluminescent device 烟台显华光电材料研究院有限公司 2020-04-21 CN disclosed
CN-106467550-B Dibenzo six-membered ring substituted compound with xanthone as core and application thereof 江苏三月光电科技有限公司 2020-03-27 CN disclosed
CN-107068910-B A kind of organic electroluminescence device of the compound containing xanthone and its application 中节能万润股份有限公司 2019-07-19 CN disclosed
CN-106220638-B A kind of compound and its application based on xanthone 中节能万润股份有限公司 2018-06-26 CN disclosed
CN-107068910-A A kind of organic electroluminescence device of compound containing xanthone and its application 中节能万润股份有限公司 2017-08-18 CN disclosed
CN-106467550-A A kind of dibenzo hexatomic ring substituted compound with xanthone as core and its application 江苏三月光电科技有限公司 2017-03-01 CN disclosed
CN-106220638-A A kind of compound based on xanthone and application thereof 中节能万润股份有限公司 2016-12-14 CN disclosed