Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 7/20 | 0.52 |
| ▸ | AVPR1A | P37288 | 7/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | RAD52 | P43351 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 3/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | HRH2 | P25021 | 1/20 | 0.48 |
| ▸ | HTR1D | P28221 | 1/20 | 0.48 |
| ▸ | HTR1B | P28222 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28114161 | 0.90 | ALDH1A1 (0.51) | AVPR2AVPR1AMEN1KMT2AALDH1A1 | |
| SCHEMBL28114173 | 0.79 | HTR1B (0.46) | KDM4EHTR1BHTR7HRH1 | |
| Morpholine SCHEMBL28114567 | 0.73 | SMN1; SMN2 (0.39) | AVPR2AVPR1AALDH1A1DRD2DRD3 | |
| SCHEMBL8719681 | 0.72 | ALDH1A1 (0.72) | MEN1KMT2AALDH1A1KDM4EHTR1A | |
| SCHEMBL8724501 | 0.72 | ALDH1A1 (0.72) | MEN1KMT2AALDH1A1KDM4EHTR1A | |
| SCHEMBL8720336 | 0.72 | ALDH1A1 (0.72) | MEN1KMT2AALDH1A1KDM4EHTR1A | |
| SCHEMBL8719445 | 0.72 | ALDH1A1 (0.72) | MEN1KMT2AALDH1A1KDM4EHTR1A | |
| SCHEMBL28114575 | 0.72 | KCNH2 (0.58) | — | |
| SCHEMBL8720341 | 0.70 | ADRA1D (0.65) | AVPR2AVPR1AALDH1A1KDM4EHTR1A | |
| SCHEMBL11130754 | 0.69 | ALDH1A1 (0.60) | AVPR2AVPR1AMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106146404-A | Pyridazinone derivative and application thereof | 江苏恩华药业股份有限公司 | 2016-11-23 | — | — | CN | disclosed |