SCHEMBL28114628

SCHEMBL28114628

O=S(=O)(O)C1(S(=O)(=O)O)C=CC=CC1c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.36
MAPT P10636 1/20 0.36
HPGD P15428 1/20 0.36
TSHR P16473 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL505429 0.75 EDNRA (0.32) KDM4EMAPTHPGDTSHR
SCHEMBL27602329 0.73 KDM4E (0.37) KDM4EMAPT
SCHEMBL365626 0.72 CHRNA7 (0.32)
SCHEMBL5453054 0.71 RECQL (0.31)
SCHEMBL28288987 0.70 NPC1 (0.34) MAPT
SCHEMBL4636573 0.70 LMNA (0.33) KDM4EMAPTHPGDSMN1; SMN2
SCHEMBL29038313 0.70 KDM1A (0.33) KDM4EMAPTHPGD
SCHEMBL8410542 0.70 ALDH1A1 (0.31)
SCHEMBL734440 0.70 KDM1A (0.38)
SCHEMBL23203046 0.69 CHRNA7 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106232214-A Composite polyamide membrane post-treated with nitrous acid 陶氏环球技术有限责任公司 2016-12-14 CN disclosed