Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | GALR3 | O60755 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4046351 | 0.82 | TSHR (0.44) | MAPTPOLBALDH1A1TSHRHTT | |
| SCHEMBL2437759 | 0.80 | TSHR (0.58) | MAPTPOLBALDH1A1TSHRHTT | |
| SCHEMBL27800466 | 0.79 | TSHR (0.41) | MAPTPOLBALDH1A1TSHRHTT | |
| Ammonia Solution, Strong SCHEMBL28208001 | 0.78 | TSHR (0.56) | MAPTPOLBALDH1A1TSHRHTT | |
| SCHEMBL11204503 | 0.78 | ALDH1A1 (0.46) | MAPTPOLBALDH1A1TSHRMEN1 | |
| SCHEMBL31481313 | 0.76 | MAPT (0.51) | MAPTALDH1A1TSHRHTTMEN1 | |
| SCHEMBL29664408 | 0.72 | TSHR (0.48) | MAPTALDH1A1TSHRHTTMEN1 | |
| SCHEMBL5652028 | 0.72 | TSHR (0.48) | MAPTPOLBALDH1A1TSHRHTT | |
| SCHEMBL899149 | 0.72 | TSHR (0.48) | MAPTALDH1A1TSHRHTTMEN1 | |
| SCHEMBL5864975 | 0.72 | TSHR (0.48) | MAPTALDH1A1TSHRHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106243020-A | A kind of diethylenetriamine tetrem acids paramagnetic probes for protein labeling | 南开大学 | 2016-12-21 | — | — | CN | claimed |
| CN-106243020-A | A kind of diethylenetriamine tetrem acids paramagnetic probes for protein labeling | 南开大学 | 2016-12-21 | — | — | CN | disclosed |