Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 2/20 | 0.67 |
| ▸ | CES2 | O00748 | 2/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | MITF | O75030 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | BCL9 | O00512 | 1/20 | 0.49 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.49 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8741192 | 0.86 | ALDH1A1 (0.60) | CES1CES2SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL28064881 | 0.84 | CES2 (0.54) | CES1CES2SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL11322862 | 0.84 | CES2 (0.56) | CES1CES2ALDH1A1MAPTKMT2A | |
| SCHEMBL527544 | 0.83 | KMT2A (0.71) | CES1CES2SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL7063519 | 0.82 | GAA (0.65) | CES1CES2SMN1; SMN2ALDH1A1MAPT | |
| Benzil SCHEMBL27888964 | 0.82 | CES1 (0.96) | CES1CES2SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL14877375 | 0.82 | CES1 (0.80) | CES1CES2SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL8578508 | 0.81 | GAA (0.59) | CES1CES2SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL1370034 | 0.81 | CES1 (1.00) | CES1CES2SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL2721319 | 0.80 | CES2 (0.56) | CES1CES2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106432322-A | 2-Carbonyl-2-phenylacetic acid p-nitrobenzoyl hydrazone diphenyltin complex, and preparation method and application thereof | 衡阳师范学院 | 2017-02-22 | — | — | CN | disclosed |
| CN-106336428-A | 2-carbonyl-2-phenyl acetic acid p-nitro benzoyl hydrazone dibenzyl tin complex and preparation method and application thereof | 衡阳师范学院 | 2017-01-18 | — | — | CN | disclosed |
| CN-106336426-A | 2-carbonyl-2-phenyl acetic acid p-nitrobenzoylhydrazone bis(p-methylbenzyl)tin complex and preparation method and application thereof | 衡阳师范学院 | 2017-01-18 | — | — | CN | disclosed |