Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28114808 | 0.84 | PTPN11 (0.36) | KDM4EALDH1A1MEN1KMT2APTPN11 | |
| SCHEMBL28025056 | 0.84 | ALDH1A1 (0.39) | KDM4EALDH1A1MEN1KMT2APTPN11 | |
| SCHEMBL28025606 | 0.79 | ALDH1A1 (0.40) | KDM4EALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL8922937 | 0.77 | CYP3A4 (0.43) | KDM4EALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL28114800 | 0.73 | KDM4E (0.48) | KDM4EALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL28025597 | 0.72 | ALDH1A1 (0.34) | KDM4EALDH1A1CA12CA1CA2 | |
| SCHEMBL28025040 | 0.70 | FBP1 (0.36) | KDM4EALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL12419947 | 0.70 | HPGD (0.48) | KDM4EALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL22489748 | 0.70 | KDM4E (0.54) | KDM4EALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL29136490 | 0.69 | CA1 (0.52) | KDM4EALDH1A1LMNATDP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104854087-B | Indole carboxamide derivatives as P2X receptor antagonists | 埃科特莱茵药品有限公司 | 2017-03-22 | — | — | CN | disclosed |
| CN-104812749-B | Indolecarboxamide derivant as P2X7 receptor antagonist | 埃科特莱茵药品有限公司 | 2016-12-14 | — | — | CN | disclosed |