Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | RGS12 | O14924 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.41 |
| ▸ | SNCA | P37840 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15272523 | 0.89 | CYP1A2 (0.71) | CYP1A2KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL4267066 | 0.83 | SNCA (0.44) | CYP1A2MAPTPOLBTSHRPDK1 | |
| SCHEMBL1865824 | 0.82 | CASP6 (0.55) | CYP1A2KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL15823182 | 0.81 | CYP1A2 (0.47) | CYP1A2KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL10370637 | 0.81 | CYP1A2 (0.47) | CYP1A2KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL5563733 | 0.81 | LMNA (0.43) | CYP1A2MAPTHPGDPOLBLMNA | |
| SCHEMBL11394570 | 0.79 | LOXL2 (0.47) | CYP1A2MAPTPOLBTSHRTDP1 | |
| SCHEMBL2710180 | 0.79 | MAPT (0.59) | CYP1A2KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL7418264 | 0.79 | CYP1A2 (0.57) | CYP1A2KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL231627 | 0.79 | MAPT (0.59) | CYP1A2KDM4EMAPTHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106132422-A | Adoptive cell therapy using agonists of retinoic acid receptor-associated orphan receptor gamma & related therapeutic methods | 莱斯拉公司 | 2016-11-16 | — | — | CN | disclosed |