SCHEMBL2710180

SCHEMBL2710180

O=C(O)Cc1ccc(O)c([N+](=O)[O-])c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.59
TSHR P16473 3/20 0.59
GAA P10253 3/20 0.59
KDM4E B2RXH2 3/20 0.59
POLB P06746 2/20 0.59
HPGD P15428 2/20 0.59
HSD17B10 Q99714 2/20 0.59
NFKB1 P19838 2/20 0.59
TDP1 Q9NUW8 2/20 0.59
LMNA P02545 2/20 0.59
RGS12 O14924 1/20 0.59
APEX1 P27695 1/20 0.59
THPO P40225 1/20 0.59
BLM P54132 1/20 0.59
GNAI1 P63096 1/20 0.59
PMP22 Q01453 1/20 0.59
HIF1A Q16665 1/20 0.59
CA2 P00918 2/20 0.54
MAPK1 P28482 2/20 0.53
ALDH1A1 P00352 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL231627 1.00 MAPT (0.59) MAPTTSHRGAAKDM4EPOLB
Nitric Acid SCHEMBL7984255 0.97 MAPT (0.56) MAPTTSHRGAAKDM4EPOLB
SCHEMBL7564083 0.88 POLB (0.52) MAPTTSHRGAAKDM4EPOLB
SCHEMBL6379699 0.86 GAA (0.59) MAPTTSHRGAAKDM4EPOLB
SCHEMBL2434953 0.86 GAA (0.59) MAPTTSHRGAAKDM4EPOLB
SCHEMBL1865824 0.86 CASP6 (0.55) MAPTTSHRGAAKDM4EPOLB
SCHEMBL2742575 0.85 MAPT (0.58) MAPTTSHRKDM4EPOLBHPGD
SCHEMBL13520189 0.85 POLB (0.52) MAPTTSHRKDM4EPOLBHPGD
SCHEMBL7126615 0.85 POLB (0.52) MAPTTSHRKDM4EPOLBHPGD
SCHEMBL3533309 0.83 POLB (0.51) MAPTTSHRKDM4EPOLBHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122050846-A Ischemic cerebral apoplexy risk assessment model fusing environmental exposure histology and metabonomics biomarkers and model construction method 生态环境部华南环境科学研究所(生态环境部生态环境应急研究所) 2026-05-15 CN disclosed
US-12577266-B2 Protein proximity assay in formalin fixed paraffin embedded tissue using caged haptens VENTANA MEDICAL SYSTEMS, INC. (US) 2026-03-17 US disclosed
EP-4707404-A2 QUINONE METHIDE ANALOG SIGNAL AMPLIFICATION Ventana Medical Systems, Inc. (US) 2026-03-11 EP disclosed
WO-2026044019-A1 COMPOSITIONS AND METHODS FOR TREATING INFLUENZA INFECTION LOW STEWART (US) 2026-02-26 WO disclosed
US-12559511-B2 Protein proximity assay in formalin fixed paraffin embedded tissue using caged haptens VENTANA MEDICAL SYSTEMS, INC. (US) 2026-02-24 US disclosed
EP-3492919-B1 QUINONE METHIDE ANALOG SIGNAL AMPLIFICATION VENTANA MED SYST INC (US) 2026-01-21 EP disclosed
US-20250339516-A1 METHOD AND MEANS FOR MODULATING B-CELL MEDIATED IMMUNE RESPONSES VACCINVENT GMBH (DE) 2025-11-06 US disclosed
US-20250326863-A1 METHOD AND MEANS FOR ENHANCING THERAPEUTIC ANTIBODIES VACCINVENT GMBH (DE) 2025-10-23 US disclosed
US-20250270311-A1 METHOD AND MEANS FOR MODULATING B-CELL MEDIATED IMMUNE RESPONSES VACCINVENT GMBH (DE) 2025-08-28 US disclosed
US-20250177506-A1 VACCINATION AND ANTIBODY GENERATION PLATFORM Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts (DE) 2025-06-05 US disclosed
EP-1144393-A2 HETEROCYCLIC DERIVATIVES AND THEIR USE AS INTEGRIN INHIBITOR AstraZeneca AB (SE) 2001-10-17 EP disclosed
EP-1133484-A2 HETEROCYCLIC DERIVATIVES AND THEIR USE AS INTEGRIN INHIBITORS AstraZeneca AB (SE) 2001-09-19 EP disclosed
WO-2001055141-A1 AZINE DERIVATIVES AS PESTICIDES SYNGENTA LIMITED (GB) 2001-08-02 WO disclosed
WO-2001055144-A1 ISOTHIAZOLE DERIVATIVES AND THEIR USE AS PESTICIDES SYNGENTA LIMITED (GB) 2001-08-02 WO disclosed
WO-2001055142-A1 ISOTHIAZOLE DERIVATIVES AND THEIR USE AS PESTICIDES SYNGENTA LIMITED (GB) 2001-08-02 WO disclosed
WO-2001055139-A1 ISOTHIAZOLE DERIVATIVES AND THEIR USE AS PESTICIDES SYNGENTA LIMITED (GB) 2001-08-02 WO disclosed
WO-2001055145-A1 AZINE DERIVATIVES AS PESTICIDES SYNGENTA LIMITED (GB) 2001-08-02 WO disclosed
WO-2000005223-A2 HETEROCYCLIC DERIVATIVES AND THEIR USE AS INTEGRIN INHIBITORS ASTRAZENECA AB (SE) 2000-02-03 WO disclosed
WO-2000005224-A2 HETEROCYCLIC DERIVATIVES AND THEIR USE AS INTEGRIN INHIBITOR ASTRAZENECA AB (SE) 2000-02-03 WO disclosed
US-5639457-A INTRODUCING DNA SEQUENCE CODING FOR REARRANGED ANTIBODY INTO MALE PRONUCLEUS OF FERTILIZED OVUM; IMPLANTING IN PIG OR RABBIT; TRANSGENIC OFFSPRING PRODUCE ANTIBODIES Brem, Gottfried (DE) 1997-06-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250339516-A1 METHOD AND MEANS FOR MODULATING B-CELL MEDIATED IMMUNE RESPONSES CD22, FCGR3B, FCGR2A MAPT 4255/4885TSHR 2370/4885GAA 1985/4885
US-12559511-B2 Protein proximity assay in formalin fixed paraffin embedded tissue using caged haptens PTMS, MKI67, ACP1 MAPT 4744/4885TSHR 1086/4885GAA 2180/4885
US-20250326863-A1 METHOD AND MEANS FOR ENHANCING THERAPEUTIC ANTIBODIES FCGR3B, FCGR2A, FCGR1A MAPT 265/4885TSHR 1125/4885GAA 756/4885
US-12577266-B2 Protein proximity assay in formalin fixed paraffin embedded tissue using caged haptens ACP1, AOX1, PTMS MAPT 4401/4885TSHR 1381/4885GAA 3535/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.