Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PTGIR | P43119 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12756968 | 0.89 | ALDH1A1 (0.42) | L3MBTL1ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL27596114 | 0.82 | KDM4E (0.44) | SIGMAR1KCNH2AOC3 | |
| SCHEMBL28147092 | 0.80 | L3MBTL1 (0.50) | L3MBTL1TDP1ALDH1A1LMNAMAPT | |
| SCHEMBL22461680 | 0.79 | IDO1 (0.45) | IDO1L3MBTL1MEN1KMT2ASIGMAR1 | |
| SCHEMBL8818336 | 0.77 | TAAR1 (0.43) | ALDH1A1LMNAMAPTMAPK1MEN1 | |
| SCHEMBL9278957 | 0.76 | MAOB (0.46) | IDO1ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL7966000 | 0.76 | MAOB (0.46) | IDO1ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL7389802 | 0.75 | IGF1R (0.45) | IDO1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL4891051 | 0.75 | HTR3A (0.47) | IDO1TDP1MAPTMAPK1SIGMAR1 | |
| SCHEMBL5609739 | 0.75 | CHRM2 (0.47) | IDO1L3MBTL1TDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106187816-B | A kind of fracture based on C N keys is come the method for synthesizing oxime ether class compound | 南开大学 | 2018-03-27 | — | — | CN | disclosed |
| CN-106187816-A | A kind of method that fracture based on C N key carrys out synthesizing oxime ether compounds | 南开大学 | 2016-12-07 | — | — | CN | disclosed |